Doukas DJ, Holmes J, Leonard JA: A nonsurgical approach to painful piezogenic pedal papules
Treatments include antihistamine tablets taken orally to relieve pruritus and corticosteroid creams that are applied to the papules
(Karppinen et al.
The mucosal erosions were painful, and some skin papules
formed small pustules (Figure 1, panel E).
He had a cat scratch 9 days before; the skin papule
appeared 1 day before he sought treatment.
The inside cheeks (buccal mucosa) characteristically have silverwhite, pin-sized papules
in a lacelike distribution.
A non-tender, nonpruritic eschar that measured 1 cm x 1 cm was visible on his right lower extremity (Figure 1) along with [approximately equal to]15 nontender, nonpruritic papules
on his torso, upper arms, and legs (Figure 2).
A 4 mm smooth papule
projected from the proximal nail fold of her left second toe, and a longitudinal groove on a fingernail could be traced to an additional proximal nail fold papule
Usually localized at the site of inoculation, CPXV lesions progress from a papule
through vesiculation and pustulation into an ulcerative nodule, which is covered with an elevated border with a black eschar.
A second Novartis-sponsored study showed that genital herpes lesions could be halted at the papule
stage in about one of every four patients taking 1,000 mg of famciclovir in divided doses during the first day they recognized prodromal symptoms.
Over the next 2 days, thigh tenderness and a papule
developed at the site of the original discomfort.
The lesion first appeared as a small papule
and was diagnosed clinically at another institution as a probable furuncle.
Typically the disease starts out as a single erythematous papule
or wheal that begins within hours or as long as 10-12 days after exposure to anthrax spores.