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A solid circumscribed elevation of the skin varying from less than 0.1 to 1 centimeter in diameter.



a nodular elevation of the skin; an element of a skin rash. Papules accompany certain diseases of the skin and mucous membranes. They occur in different sizes, colors, and consistencies; in shape they may be conical, hemispheric, or flat. Inflammatory papules indicate the presence in the skin of an infiltrate, as in syphilis. An example of noninflammatory papules is the thickening of the epidermis in warts.

References in periodicals archive ?
Eruptive xanthoma is characterized by an abrupt onset of crops of multiple yellowish to brownish papules that can coalesce into small plaques.
Anecdotal good results have been reported with oral dimethyl sulfoxide (DMSO), [45] D-penicillamine, [28] etretinate, [46] and acitretin, [47, 48] and carbon dioxide laser surgery have been proposed in the treatment of affected vocal cords and eyelid papules. [49] However, there are also reports of limited success or unsatisfactory results with some of these medications.
Although pain is a characteristic of this case, our patient reported burning sensation as the predominant symptom, the papules on his back were in a dermatomal pattern and there was involvement of the limbs, as well.
In a large retrospective case series, various skin abnormalities such as follicular papules, comedones, hypertrophic pilosebaceous units, angiokeratoma of Fordyce, leucoderma macules, and haemangiomas have been shown to be associated with NLCS.
Presence of significant increase in sweating on the nose and central face appears to be responsible for the secondary changes like erythema and erythematous papules [9].
This patient was found to be in the severe stage of ILD associated with DM because of having some prognostic factors including not only hypoxemia with anti-MDA5-Ab positivity but also refractory ulcerative eruptions as well as palmer papules. In fact, it has been previously described that existing cutaneous ulceration and/or palmer papules are associated with acute progression of ILD in DM [6, 7]; furthermore, the positive correlation between severity of ulcerative cutaneous involvement and anti-MDA5-Ab has been demonstrated [6, 19, 20].
Clinical appearance: annular, brown, hyperkeratotic 0.5 -1 cm in diameter papules on the forearms.
The condition may sound relatively benign in dogs, but papules can develop into painful lesions, hair loss or worse--a life-threatening staphylococcus infection.
The PPP Global Awareness Survey is the first initiative to understand if indeed there is bias in public perception about pearly penile papules.
PLC is characterised by small, scaly papules with no evolution to necrotic lesions.1,4
Clinically, syringomas appear as small, multiple, firm, skin-colored-to-yellowish papules, 1 to 3 mm in diameter (2).
The spectrum of idiopathic ultraviolet-induced dermatoses includes the most severe variant, polymorphous light eruption (PMLE), in which erythematous papules, papulovesicles, and plaques form from a delayed type IV hypersensitivity reaction to the sun.