And the risk is not only from RSV That said, RSV remains a player in some patients (particularly NMD patients) despite palivizumab prophylaxis, highlighting the need for RSV as well as parainfluenza
infection in normal, healthy patients is not a life-threatening disease.
Among those, 175 children positive for any influenza A or B virus; RSV A-B, rhinovirus, adenovirus, metapneumovirus A-B, parainfluenza
virus 1 and 3, bocavirus, Mycoplasma pneumoniae, enterovirus, coronavirus OC43, 229E, and HKU1 were shown to be infected dually with influenza A and B viruses.
It detects 22 viral and bacterial targets including influenza A virus, influenza A virus subtype seasonal H1, influenza A virus subtype seasonal H3, influenza A virus subtype swine-origin H1N1pdm09, influenza B virus, RSV A and B, parainfluenza
viruses types 1 to 4, adenovirus, hMPV, rhinovirus/enterovirus, human coronavirus- (HCoV-) 229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, human bocavirus, Chlamydophila pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila (Table 1).
Variable Value Age range (mean) 25-97 (54.6) Prodromal symptoms 13/15 (87%) Stridor 9/15 (60%) Need for artificial airway 7/15 (47%) Nebulized epinephrine 11/15 (73%) Steroid administration 12/15 (80%) Antibiotic administration 8/15 (53%) Organisms identified* 5/15 (33%) Hospital days range (mean) 3-35 (9.1) ICU admission 13/15 (87%) Steeple signA 11/12 (92%) * Parainfluenza
, Haemophilus, influenza, Streptococcus, respiratory syncytial virus.
To our knowledge, there are only two cases reported of pericardial effusion associated with parainfluenza
viruses in children and none of them in the neonatal period.
In allogeneic hematopoietic stem cell transplant (HSCT) recipients, parainfluenza
(PIV) virus can cause varying spectrum of respiratory illness, ranging from self-limited upper respiratory tract infections (URTI) to severe, life-threatening lower respiratory tract infections (LRTI) [1, 2].
Another member of the Paramyxoviridae family with the same type of genome as RSV is parainfluenza
To the Editor: Parainfluenza
virus 5 (PIV5), family Paramyxoviridae, genus Rubulavirus, was previously known as simian virus 5 because of its discovery in primary monkey kidney cells in 1954 (1).
Background: Although human parainfluenza
virus (HPIV) has been determined as an important viral cause of acute respiratory infections (ARIs) in infants and young children, data on long-term investigation are still lacking to disclose the infection pattern of HPIV in China.