Histology of PR reveals focal parakeratosis
in the epidermis in mounds with exocytosis of lymphocytes, variable spongiosis, mild acanthosis, and a thinned granular layer.
The development of branches may be an adaptation to increase surface area and overcome decreased absorption due to parakeratosis
Other histological features rarely reported are parakeratosis
, the presence of large lobules of sebocytes in the lower part of the tumor that occasionally undergo cystic degeneration, the scattering of individual sebocytes or small clusters throughout the lesion, sebaceous cell clusters occasionally opening onto the skin surface, and increased melanin pigment (1-6, 8).
A skin biopsy demonstrated psoriasiform dermatitis with alternating areas of orthokeratosis and parakeratosis
(the presence of keratinocyte nuclei within the stratum corneum where nuclei typically aren't found).
Histological examination from hyperkeratotic papules reveals acanthosis with parakeratosis
in epidermis due to rapid proliferation and differentiation of keratinocytes.
5,12) The overlying epidermis can display a host of changes, including acanthosis, hyperkeratosis, parakeratosis
, rete ridge flattening, entrapment of adnexal structures, and, rarely, ulceration.
Histologic findings in DLE include epidermal atrophy, basal membrane cell vacuolization, hyperkeratosis, parakeratosis
, corneal plugs, pseudoscysts, and acanthosis.
Histologic examination of the excised material revealed sections of soft tissue covered by stratified squamous epithelium with parakeratosis
The purpose of this study is to show the significant association of squamous metaplasia (the precursor for cervical cancer), hyperkeratosis, and parakeratosis
, and as the Pap smear finding in patients with uterine prolapse, which is sparsely represented in the literature despite the high incidence of the later.
(retention of nuclei in stratum corneum).
The epidermis often shows edema with spongiosis and increased cell layers with parakeratosis
, hyperkeratosis, and dyskeratosis.