parasympathomimetic


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parasympathomimetic

[‚par·ə¦sim·pə·thō·mi′med·ik]
(pharmacology)
Of drugs, having an effect similar to that produced when the parasympathetic nerves are stimulated.
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In clinical practice, atropine, a nonselective muscarinic receptor blocker, is employed to prevent the parasympathomimetic effects induced by neostigmine when the anticholinesterase agent is clinically used to reverse the blockage of neuromuscular transmission caused by non-depolarizing muscular relaxants (Barrio, Miguel, Garcia, & Pelegrin, 2007).
Parasympathomimetic effect of shilajit accounts for relaxation of rat corpus cavernosum.
Nicotine is a nicotinic acetylcholine receptor (nAChR) agonist with parasympathomimetic effects.
Immune: anti-inflammatory (inhibits synthesis of prostaglandins and chemotaxis of leukocytes), antiallergic (reduces histamine release from mast cells); ANS: sympatholytic, parasympathomimetic;
[2] At physiological levels, digoxin slows the sinus rate, prolongs the AV node refractory period and has parasympathomimetic effects.
The bioisosteres so obtained are less potent and enhanced toxicity, hence there is no further encouragement in the synthesis of direct acting parasympathomimetic. As the size of onium ion increased, the pharmacological activity was decreased [55].
Cardiac glycosides also can be prescribed as anti-arrhythmics for certain common atrial dysrhythmias, such as atrial flutter and atrial fibrillation; its parasympathomimetic actions increase the vagal tone to the sinoatrial and AV node.