parent compound

parent compound

[′per·ənt ‚käm‚pau̇nd]
(chemistry)
A chemical compound that is the basis for one or more derivatives; for example, ethane is the parent compound for ethyl alcohol and ethyl acetate.
References in periodicals archive ?
The synthesis was initiated by the coupling of 2-furyl(1-piperazinyl)methanone (1) with 3,5-dichloro-2-hydroxybenzenesulfonyl chloride (2) under dynamic pH control in aqueous alkaline medium to form parent compound, {4-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-1-piperazinyl}(2-furyl)methanone (3).
The higher value of MDIPU than its parent compound in the soil column leachate also revealed that MDIPU is potentially more mobile than IPU.
Parent compound 3a was synthesized as light grey powder with yield of 92 % and melting point of 152-154 AdegC.
In addition, both LADR-7 and LADR-8 consistently demonstrated statistically significant superiority over both the control group and the parent compound AE at its maximum tolerated dose in nine of the nine models tested.
Indeed, phase I metabolism may generate metabolite(s) with increased, decreased or similar activity to that of the parent compound. Moreover, the first-generation metabolite(s) may also be substrate(s) of metabolic enzymes, further altering their activities.
Along with compound 1, we also tested the effects of isofraxidin (7-hydroxy-6,8-dimethoxycoumarin), the parent compound of compound 1.
But the final inhibition (28.93%) was less than the initial inhibition (36.97%), which means that the metabolites products of indole were ultimately less toxic than the parent compound indole.
Compared to the parent compound, the resolved Na[Cu[([L.sub.1]).sub.3]] demonstrated a greatly higher activity only against S.
In silico approach was undertaken to qualify this impurity in relation to the genotoxicological profile of the parent compound, bisoprolol [3].
It is often considered the parent compound of several naturally occurring organic compounds.
The majority of these designer drugs are derived from the parent compound cathinone, the active ingredient of the plant khat (Catha edulis).