(7) It is, therefore, vitally important that the efficacy of
paromomycin in the treatment of cutaneous leishmaniasis be fully elucidated.
Safety and efficacy of short course combination regimens with AmBisome, miltefosine and
paromomycin for the treatment of visceral leishmaniasis (VL) in Bangladesh.
As for treatment, 12 patients were treated with topical
paromomycin therapy with the addition of gentamicin to a petroleum base, and one was observed without treatment, she added.
As for treatment, 12 patients were treated with topical
paromomycin therapy with the addition of gentamicin to a petroleum base, and one was observed without treatment, she added."All patients are recovering well with no recrudescence of disease and no appearance of new lesions."
Intravenous tinidazole, and or intravaginal
paromomycin, intazoxanide can be tried in refractory cases.
Specifically,
paromomycin (PMM), a clinically approved aminoglycoside for the treatment of various bacterial and parasitic infections, is currently used alone [3] or in combination with other drugs [4, 5] to treat both cutaneous and visceral leishmaniasis, the latter a fatal disease.
Koprowski et al., "EPR studies of free radicals decay and survival in gamma irradiated aminoglycoside antibiotics: sisomicin, tobramycin and
paromomycin," European Journal of Pharmaceutical Sciences, vol.
Amphotericin B and
Paromomycin, two other currently available second-line antileishmanial treatments [10, 11], also present significant shortcomings with regard to toxicity, cost, and duration of treatment.
Oral administration of miltefosine and the IM administration of
paromomycin and pentamidine are also used for leishmaniasis [37, 40-42].
The patient took
paromomycin, an aminoglycoside antibiotic, from symptom onset until a pediatric outpatient visit on June 16, at which time a stool specimen was collected.
The traditional anti-Giardial treatment in sheep includes the usage of fenbendazole (10,11), albendazole (12), secnidazol (13,14) and
paromomycin (15) resulting in a clinical benefit in treated lambs.
Several antibiotics such as Cefazolin, Vancomycin,
Paromomycin and Clindamycin are also set to get ceiling prices.
