Nasdaq: SEPR) announced that positive data from three Phase III studies presented today at the 8th European Congress of Epileptology in Berlin, demonstrated that eslicarbazepine acetate, a novel once-daily anti-epileptic agent, significantly reduced the frequency of
partial seizures in patients with refractory partial epilepsy, in combination with other anti-epileptic agents.
In RESTORE 2, the median reduction in 28-day total
partial seizure frequency from baseline to the end of the double-blind period in the ITT population was 39.
The ganaxolone program currently consists of four clinical studies, one infantile spasms and one adult
partial seizure study as well as open label extensions for each study.
Positive data from three phase III studies presented today at the 8th European Congress of Epileptology, Berlin, Germany, demonstrated that Zebinix(TM) (1) (eslicarbazepine acetate), a novel once daily anti-epileptic agent, significantly reduced the frequency of
partial seizures in patients with refractory partial epilepsy, in combination with other anti-epileptic agents.
50 percent reduction in
partial seizure frequency during the 19-week treatment phase of the study was also significantly higher in the Lamictal XR group compared to placebo (42.
19]]) was to compare the efficacy and tolerability of perampanel, administered in one daily dosage with that of the placebo in combination therapy in patients aged 12 and above with
partial seizures uncontrolled by one to three AEDs.
Patients must have had six or more
partial seizures over the 56-day baseline phase (BP).
The antiepileptic drug (AED) Trileptal (R) (oxcarbazepine, Novartis Pharmaceuticals Corporation) maintains efficacy during long-term treatment in patients with
partial seizures, according to data from the two-year open-label extension phases of three studies.
This article will provide nurses with knowledge about patients with complex
partial seizures originating in the temporal lobe and possible cardiac arrhythmias associated with these seizures (Opherk et al.
A patient experiencing a complex
partial seizure will often stare off into space.
Miranda believes the symptoms that lead to the diagnosis of autism, such as language regression and behavioral disturbances, are frequently caused by a form of epilepsy--a treatable,
partial seizure disorder that is virtually impossible to see with the naked eye, and is often missed by the current test used to detect it.
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Partial Seizure Global Clinical Trials Review, H2, 2014 https://www.
