partition coefficient


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partition coefficient

[pär′tish·ən ‚kō·i‚fish·ənt]
(analytical chemistry)
In the equilibrium distribution of a solute between two liquid phases, the constant ratio of the solute's concentration in the upper phase to its concentration in the lower phase. Symbolized K.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The penetration will be "easier" for xenobiotics with partition coefficients similar to the partition coefficient of the stratum corneum.
Only three properties had potentially reproducible models in >50% of the published articles (Table 1): for hydrolysis, 88%; for octanol-air partition coefficient, 59%; and for octanol-water partition coefficient, almost 52%.
Sohlenius, Solid/liquid Partition Coefficients (Kd) for Selected Soils and Sediments at Forsmark and Laxemar-Simpevarp.
4 gives an insight into the performance of the algorithm that the proposed algorithm has high value of Partition Coefficient ([V.sub.pc]) and low value of Partition Entropy ([V.sub.pe]), which shows that the proposed GcsFCM algorithm is performed consistently on all the images of the four data volumes.
At concentrations in the environment, adsorption isotherms of organic compounds in the soil can be considered linear, thus being represented by the expression 2, in which S is the adsorbed fraction (M [M.sup.-1]), [C.sub.e] is the concentration of the chemical substance in the liquid phase ([L.sup.3] [M.sup.-1]) and KD is the soil-solution partition coefficient ([L.sup.3] [M.sup.-1]).
The removal efficiency, ([phi]) and partition coefficient, ([K.sub.PC]) of the hydrogels were calculated as;
This is because the partition coefficient of solvent is much higher for the spray with pH 9.5, whereas the alkaline spray may have higher reaction rate with gaseous iodine.
According to references [30, 31], heat partition coefficient is
Octanol-Water Partition Coefficient. The octanol-water partition coefficient (log P) of a compound always reflects its lipid solubility and correlates with its pharmacokinetics, such as cell membrane permeability and tissue distribution, according to the studies of quantitative structure-activity relationship [19].
Semiempirical partitioning models, such as the lattice strain model [41, 42], aim to determine a set of partition coefficients ([D.sub.i]) for ion i where, for example, the partitioning of a trace ion between fluid and mineral is described by
Oil to water partition coefficient of a substance gives idea about its lipophilicity and hydrophobicity.7 Excipients utilised should have ideal characteristics shown in Table 3.9,10,11