The penetration will be "easier" for xenobiotics with partition coefficients
similar to the partition coefficient
of the stratum corneum.
Only three properties had potentially reproducible models in >50% of the published articles (Table 1): for hydrolysis, 88%; for octanol-air partition coefficient
, 59%; and for octanol-water partition coefficient
, almost 52%.
Sohlenius, Solid/liquid Partition Coefficients
(Kd) for Selected Soils and Sediments at Forsmark and Laxemar-Simpevarp.
4 gives an insight into the performance of the algorithm that the proposed algorithm has high value of Partition Coefficient
([V.sub.pc]) and low value of Partition Entropy ([V.sub.pe]), which shows that the proposed GcsFCM algorithm is performed consistently on all the images of the four data volumes.
At concentrations in the environment, adsorption isotherms of organic compounds in the soil can be considered linear, thus being represented by the expression 2, in which S is the adsorbed fraction (M [M.sup.-1]), [C.sub.e] is the concentration of the chemical substance in the liquid phase ([L.sup.3] [M.sup.-1]) and KD is the soil-solution partition coefficient
The removal efficiency, ([phi]) and partition coefficient
, ([K.sub.PC]) of the hydrogels were calculated as;
This is because the partition coefficient
of solvent is much higher for the spray with pH 9.5, whereas the alkaline spray may have higher reaction rate with gaseous iodine.
According to references [30, 31], heat partition coefficient
Octanol-Water Partition Coefficient
. The octanol-water partition coefficient
(log P) of a compound always reflects its lipid solubility and correlates with its pharmacokinetics, such as cell membrane permeability and tissue distribution, according to the studies of quantitative structure-activity relationship .
Semiempirical partitioning models, such as the lattice strain model [41, 42], aim to determine a set of partition coefficients
([D.sub.i]) for ion i where, for example, the partitioning of a trace ion between fluid and mineral is described by
Measurement by the Stir-Flask Method.
Oil to water partition coefficient
of a substance gives idea about its lipophilicity and hydrophobicity.7 Excipients utilised should have ideal characteristics shown in Table 3.9,10,11