pathogenicity island


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pathogenicity island

[‚path·ə·jə′nis·əd·ē ‚ī·lənd]
(genetics)
A deoxyribonucleic acid cluster commonly containing genes associated with pathogenesis. Also known as virulence cassette.
References in periodicals archive ?
Structural and sequence diversity of the pathogenicity island of uropathogenic Escherichia coli which encodes the USP protein.
Pounder, "Conservation of the cag pathogenicity island of Helicobacter pylori: associations with vacuolating cytotoxin allele and IS605 diversity," Gastroenterology, vol.
These include CTX genetic element encoding the genes for CT and other accessory toxins, vibrio pathogenicity islands (VPIs) responsible for the synthesis and expression of the major type of adhesion pili (toxin coregulated pilus or TCP) and certain other virulence factors, etc.
Diversos factores de virulencia de Salmonella estan codificados por genes que se encuentran agrupados en las islas de patogenicidad SPI (del ingles: Salmonella Pathogenicity Islands).
Researchers observed how pathogenicity islands underwent an unprecedented evolutionary adaptation to be able to transfer pathogens to other innocuous bacteria and thus transform them into virulent bacteria.
The revised definition is based primarily on the presence of the LEE pathogenicity island, which is a marker of attaching-effacing capacity.
Horizontal gene transfer can also lead to the acquisition of pathogenicity islands, large clusters of genes required for pathogen virulence.
The epidemic strain is unusual in that it contains a unique 89-kb (89K) pathogenicity island (PAI) (3,6,7).
Intestinal epithelial cells are normally nonphagocytic; however, Salmonella have the capacity to invade these cells through a sophisticated machinery termed a type 3 secretion system (T3SS); the genes encoding the T3SS are located on Salmonella pathogenicity island 1 (SPI-1) [36, 37].
STEC-EPEC oligonucleotide microarray: a new tool for typing genetic variants of the LEE pathogenicity island of human and animal Shiga toxin-producing Escherichia coli (STEC) and enteropathogenic E.