The IPPF is incredibly grateful for their service to the pemphigus and pemphigoid
community," said IPPF Awareness Program
Specifically, it helps distinguish bullous pemphigoid
and epidermolysis bullosa acquisita.
Our study demonstrated that the frequency of diagnosis of skin bullous lesions in city of Sari is almost similar to other related studies and the most common diagnoses are pemphigus vulgaris, bullous pemphigoid
, dermatitis herpetiformis and pemphigus foliaceus.
Among the various bullous disorders, only 4 cases of bullous pemphigoid
(2%) and 3 cases of pemphigus vulgaris (1.
Bullous systemic lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid
antigen 1, laminin-5, laminin-6, and type VII collagen.
Furthermore patients with uncontrolled medical problems like diabetes mellitus, bleeding disorders, pemphigus, pemphigoid
, lupus erythematosus were also excluded.
There are conflicting arguments on whether it is a symptom of oral lichen planus (Figure 3), mucous membrane pemphigoid
(Figure 4), or a clinical manifestation of these diseases (12, 18).
is a disease of the elderly and presents as pruritic tense bullae favoring the flexural creases, and sometimes as erythematous urticarial plaques.
gestationis and intrahepatic cholestasis of pregnancy--can cause negative effects on the fetus
The first attempt to classify these conditions was made by Holmes and Black in 1982-83 who classified them into: a) Pemphigoid
Gestationis (PG) or Herpes Gestationis(HG), b) Polymorphic Eruption of Pregnancy (PEP) or Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP), c) Prurigo of Pregnancy (PP) and d) Pruritic Folliculitis of Pregnancy (PF).
Mucous membrane pemphigoid
is a chronic inflammatory autoimmune disease process that is characterized by subepithelial blistering, primarily of the mucosa, with linear deposition of Immunoglobulin G (IgG), Immunoglobulin A (IgA), and Complement 3 (C3) at the basement membrane .
Besides the diagnosis of SOIJA, in bullous ENL other bullous disorders like pemphigus vulgaris, bullous drug eruption or bullous pemphigoid
should be ruled out when there is involvement of oral mucosa and acantholytic cells are found on a Tzanck test.