pentasaccharide

pentasaccharide

[‚pen·tə′sak·ə‚rīde]
(biochemistry)
A carbohydrate which, on hydrolysis, yields five molecules of monosaccharides.
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References in periodicals archive ?
The backbone of the polysaccharide chain consists of repeating pentasaccharide units formed by two glucose units, two mannose units, and one glucuronic acid unit.
13: Low Molecular Weight Heparin or Pentasaccharide Indications for VTE Treatment 133 Table 6.
the pentasaccharide) led to the development of fondaparinux, a synthetic antithrombotic drug that mimics the essential pentasaccharide sequence (3).
Fondaparinux (Arixtra) is a synthetic sulfated pentasaccharide that inhibits factor Xa indirectly by binding to antithrombin III.
Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide.
20,21) Fondaparinux is a synthetic pentasaccharide that inhibits factor Xa, and therefore could be used in patients known to be hypersensitive to LMWH preparations.
A particular unique, highly sulphated pentasaccharide sequence that is present in 30% of heparin molecules accounts for the anticoagulant effect of heparin.
Fondaparinux is a heparin pentasaccharide analogue that does not bind to platelet-factor 4 and thus should not cause HIT.
Mario Pinto, from Simon Fraser University, David Bundle and Mary Chervenak from the University of Alberta, and Nand Vyas, Meenakshi Vyas and Florante Quiocho from Baylor College of Medicine in Houston, TX, have shown that the binding modes of the pentasaccharide that elicits the immune response in the first place are significantly different from the synthetic octapeptide.