pentobarbital sodium

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pentobarbital sodium

[¦pen·tō′bär·bə‚tȯl ′sōd·ē·əm]
(pharmacology)
C11H17N2NaO3 A short- to intermediate-acting barbiturate; used as a hypnotic and sedative drug. Also known as sodium pentobarbitone.
References in periodicals archive ?
At postnatal day 160, animals were fasted overnight and killed by decapitation following anaesthesia with sodium pentobarbitone (60 mg/kg, IP).
Rats were anesthetized with pentobarbitone sodium (60 mg/kg dose i.p.) and a 23-gauge cannula was stereotaxically inserted into the piriform cortex 2 mm dorsal to the middle cerebral artery (0.2 mm anterior, -5.2 mm lateral, and -5.9 mm ventral) as previously described [4,15,16].
At the end of four weeks, the rats were anaesthetized by administering single intraperitoneal injection of sodium pentobarbitone (50 mg/100 g body weight)9.
(11) After 10 days of treatment, rats were anaesthetised with sodium pentobarbitone (60 mg/kg, intraperitoneal) and received heparin (200 IU intravenously (IV)).
The introduction of oral barbiturates, such as pentobarbitone (Nembutal) and quinalbarbitone (Seconal), continued this trend in the 1930s.
2003); however, most of them are chemical products such as magnesium sulfate, 2-phenoxyethanol, pentobarbitone, and benzocaine.
A sterilized cotton pellet weighing 10 +- 0.5mg [30], 30mg [22] or 50mg [28] is implanted subcutaneously in rats anaesthetized by intraperitoneal injection of sodium pentobarbitone (30 mg/kg body wt) .
Anaesthesia was induced by sodium pentobarbitone (Nembutal[R], CAVE, France) at a dose of 60 mg/ kg (ip).
An alcoholic extract of CP was found to cause an antagonist effect against amphetamines and tremorine, a potentiation of the acetylcholine effect of pentobarbitone induced hypnosis and morphine analgesia, without having own sedative properties.
The drugs, a powerful barbiturate called Pentobarbitone Sodium, are used by vets and RSPCA staff to put animals to sleep and doctors warned could be lethal if taken by people.
Four rabbits, 2 with each implant type, were humanely euthanased at 1, 3 and 6 months after surgery with intravenous pentobarbitone (Euthanase[R], Centaur Laboratories, Isando, South Africa).