peptide map


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peptide map

[′pep‚tīd ‚map]
(cell and molecular biology)
A fragmentation pattern generated by digestion of a particular protein with proteolytic enzymes of known specificity; used in protein identification.
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To identify the Va134Leu polymorphism in the activation peptide of FXIIIA, blood samples from 10 healthy volunteers were subjected to DPD analysis and individual peptide maps were generated.
Protein Metrics supplies software to automate multiple aspects of biotherapeutic protein analysis, including the ability to integrate peak areas and track potential quality attributes for batches of therapeutic protein peptide maps, characterize and quantify post-translation modifications (PTMs) and sequence variants.
Byomap can simultaneously align and quantitatively compare up to ten peptide maps to an annotated reference map, flagging peaks with out-of-tolerance intensities.