perazine


Also found in: Medical.

perazine

[′per·ə‚zēn]
(pharmacology)
C20H25N3S A crystalline compound, melting at 51-53°C; used in medicine as a tranquilizer.
References in periodicals archive ?
The research question is whether perazine can effectively treat schizophrenia.
The electrochemical quantitative analysis of many drugs has been carried out by polarographic techniques, some of them are benzodiazepines (bromazepam, chlordiazepoxide, clonazepam, diazepam, dipotassium chlorazepate, flunitrazepam; flurazepam, lorazepam, medazepam, midazolam, nitrazepam, oxazepam, pinazepam, prazepam, temazepam, triazolam, clobazam), meprobamate, phenothiazine- thioxantene- and butyrophenone-derivatives, sulpirid, reserpine, imipramine, thioridazine, amitriptyline, imipramine, opipramol, doxepine, chlorpromazine, levopromazine, perazine, prothipendyl, chlorprothixene, triperidol, methamphetamine [5].
The electrochemical quantitative analysis of many drugs has been carried out by polarographic techniques, some of them are benzodiazepines (bromazepam, chlordiazepoxide, clonazepam, diazepam, dipotas-sium chlorazepate, flunitrazepam; flurazepam, lorazepam, medazepam, midazolam, nitrazepam, oxazepam, pinazepam, prazepam, temazepam, triazolam, clobazam, meprobamate, phenothiazine thioxantene and butyrophenone-derivatives, sulpirid, reserpine, imipramine, thioridazine, amitriptyline, imipramine, opipramol, doxepine, chlorpromazine, levopr- omazine, perazine, prothipendyl, chlorprothixene, triperidol, methamphetamine [5].
For example, the AGATE researchers reported that the "atypical" drugs amisulpride and zotepine (not approved for use in the United States) and risperidone were indistinguishable from "typical" fluphenazine in terms of the risk of extrapyramidal side effects, whereas perazine, a "typical" antipsychotic available in Europe, had a risk profile lower than most drugs in the "atypical" class.
Predictors of neuroleptic treatment response in acute schizophrenia: results of a treatment study with perazine.