Pericyte


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pericyte

[′per·ə‚sīt]
(histology)
A mesenchymal cell found around a capillary; it may or may not be contractile.

Pericyte

 

(also Rouget cell), a branching cell in the wall of a blood-carrying capillary. The cytoplasm of pericytes is characterized by the presence of fibrillar elements and micropinocytotic vesicles, whose membranes exhibit adenosine triphosphatase activity. The outgrowths of pericytes surround the capillaries and, penetrating the basement membrane, either come into contact with the endothelial cells or are separated from the cells by a narrow space. Some scientists consider pericytes to be partially differentiated cells, capable of being transformed into other cellular elements of connective tissue. Others consider pericytes to be differentiated contractile elements, capable of changing the lumen of the capillary. Still others admit the existence of various types of pericytes, capable of regenerative or contractile functions.

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In the course of DME, Muller glial cell and pericyte dysfunction can be involved.
Those inflammatory mediators released during sleep restriction may directly induce pericyte detachment from the vessel wall ensuing blood-brain barrier disruption (for review see Hurtado-Alvarado, 2014 [116]).
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis," American Journal of Pathology, vol.
Some SFTs are incorrectly characterized as hemangiopericytomas due to pericyte differentiation [30, 31].
Stromal Matrix Metalloproteinase-9 Regulates the Vascular Architecture in Neuroblastoma by Promoting Pericyte Recruitment.
The diagnosed of HPC is controversial and currently concept about HPC is that the tumor is arised from fibroblast rather than pericyte.
Pericyte of a teleost fish: Ultrastructure, position, and role in neoplasia as revealed by a fish model.
1,2] A pericyte is a cell found in the wall of capillaries, originally described by Stout and Murray.
Role of CD44+ stem cells in mural cell formation in the human choroid: evidence of vascular instability due to limited pericyte ensheathment.
They reported that there is a relationship between pericytes and pulmonary fibrosis and analysis revealed that pericyte markers increased in fibrotic regions.
2012) showed that [alpha]-SMA expressing cells were present around capillaries and can thus act as a pericyte marker.