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Related to peripheral ossifying fibroma: Peripheral giant cell granuloma


A benign tumor composed primarily of fibrous connective tissue. Also known as fibroid tumor.



a mature benign tumor of connective tissue, which can occur in any part of the body. Fibromas may be diffuse or encapsulated, depending on the nature of their growth. Fibroblasts are the source of fibromas, hence their other name, fibroblastomas. The symptoms and the course of a fibroma depend on the site and the rate of growth. Malignant degeneration sometimes occurs. Fibromas are treated surgically.

References in periodicals archive ?
Kendrick F, Waggoner WE Managing a peripheral ossifying fibroma.
Comparison between the peripheral ossifying fibroma and peripheral odontogenic fibroma.
Localized gingival enlargement associated with alveolar process expansion', peripheral ossifying fibroma coincident with central odontogenic fibroma.
Key Words: Peripheral Ossifying Fibroma Cemento Ossifying Fibroma Gingival Growth Cementum like Calcifications.
Peripheral ossifying fibroma (POF) is one of the several common reactive hyperplastic inflammatory lesions of the gingiva.
7, 8, 9, 10) Unlike GCF, peripheral ossifying fibroma is found only in the gingiva, occurs more in females, and is thought to arise from the periodontal ligament.
The etiopathogenesis of this tumor is not clear; however, the pluripotent cells of the periodontal ligament have the apparent ability to transform into osteoblasts, cementoblasts or fibroblasts, in response to irritants such as calculus, bacterial plaque, orthodontic appliances, illadapted crowns, and irregular restorations, and are therefore, capable of producing a unique inflammatory hyperplasia, the peripheral ossifying fibroma.
Buchner A, Hansen LS: The histomorphologic spectrum of peripheral ossifying fibroma.
The histological study of the specimen after simple resection confirmed the diagnosis of peripheral ossifying fibroma.
Peripheral ossifying fibroma (POF) is a reactive gingival nodule composed of a cellular fibroblastic connective tissue stroma associated with the formation of randomly dispersed foci of mineralized product consisting of bone, cementum-like tissue, or dystrophic calcification.

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