periplasm


Also found in: Dictionary, Medical, Wikipedia.
Related to periplasm: peptidoglycan, lipopolysaccharide, teichoic acid

periplasm

[′per·ə‚plaz·əm]
(cell and molecular biology)
The region between the cytoplasmic and outer membranes of a cell.
Mentioned in ?
References in periodicals archive ?
cholerae after its assembly in the periplasm (27,28).
Since periplasmic targeting of antigens has been shown to be effective in delivering heterologous antigens, we investigated whether the expression of chlamydial outer membrane protein, PorB, in the periplasm of VCG would lead to a robust antigen expression.
The PhoA component of this fusion construct shows whether IcsA has been secreted across the cytoplasmic membrane to the periplasm of Shigella since the PhoA is only active in the periplasm.
The TonB protein spans the periplasm and is anchored to the cytoplasmic membrane and interacts with receptors in the outer membrane to facilitate the uptake of several nutrients or growth factors, including iron-siderophore complexes.
As late as the early 1970s science was unaware that the periplasm existed; now we know it is the extracytoplasmic compartment found in gram-negative bacteria figuring in protein transport, folding, cell architecture, cell division, stress responses and other essential functions.
Chou, "Roles of DegP in Prevention of Protein Misfolding in the Periplasm upon Overexpression of Penicillin Acylase in Escherichia coli," Journal of Bacteriology 185 (2003), pp.
Drug is actively extruded from the cytoplasm or cytoplasmic membrane across the periplasm and outer membrane to the cell exterior; the energy for this process is derived from the proton gradient across the membranes.
Curli formation requires a specialised and mechanistically unique transporter in the bacterial outer membrane, as well as two soluble accessory proteins thought to facilitate the safe guidance of the curli subunits across the periplasm and to coordinate their self-assembly at cell surface.