phage


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phage:

see bacteriophagebacteriophage
, virus that infects bacteria and sometimes destroys them by lysis, or dissolution of the cell. Bacteriophages, or phages, have a head composed of protein, an inner core of nucleic acid—either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA)—and a
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.

phage

[fāj]
(virology)

phage

A program that modifies other programs or databases in unauthorised ways; especially one that propagates a virus or Trojan horse. See also worm, mockingbird. The analogy, of course, is with phage viruses in biology.
References in periodicals archive ?
The new facility is located at the company's headquarters in Ness Ziona and will support clinical manufacturing of BiomX's candidate phage products and in the future could be expanded to support commercial manufacturing needs.
Phages are the most abundant biological particles on the planet and are typically found wherever bacteria reside.
Increasing bacterial resistance and the urgent need for novel antimicrobial therapeutics has reignited interest within the scientific community about phage therapy.
They suggested that merely the protection of a bacteriophage lysate from evaporation and bacterial contamination suffices to maintain phage titer with the passage of time during storage.
We determined the complete sequences of the Stx1a and Stx2c phages from strain 980938 (from an asymptomatic carrier) and the Stx2c phage from strain 981447 (from a patient with bloody diarrhea) as described previously (39).
RFLP were take place by restriction digestion analysis for the purified DNA isolated from phage isolates.
"We hypothesize that inflammation or other host defenses alter phage abundances during colitis," the study said.
Locus is the world leader in CRISPR-engineered phage therapeutics, uniquely leveraging the powerful Type I CRISPR-Cas3 system to specifically destroy the DNA of target bacteria cells, quickly killing them.
A phage cocktail is effective within hours, not days, and in very small doses.
To understand how phage therapy works, it helps to know a little biology, starting with the distinction between bacteria and viruses.