phagosome

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phagosome

[′fag·ə‚sōm]
(cell and molecular biology)
A closed intracellular vesicle containing material captured by phagocytosis.
References in periodicals archive ?
Role of the Brucella suis lipopolysaccharide O antigen in phagosomal genesis and in inhibition of phagosome-lysosome fusion in murine macrophages.
Metal transporters, NRMP-2 and DMT-1 transport the recovered iron through the phagosomal membrane to the cytoplasm to be stored in the macrophage bound to ferritin.
Intracellular fate of Mycobacterium avium: use of dual-label spectrofluorometry to investigate the influence of bacterial viability and opsonization on phagosomal pH and phagosomelysosome interaction.
The methods in autophagy will allow the reader to find appropriate techniques to identify, monitor, and quantify autophagic processes, while the methods devoted to phagocytosis will provide researchers with several modern techniques for in vivo and in vitro studies of phagosomal organelles.
Identification of a PEST-like motif in listeriolysin O required for phagosomal escape and for virulence in Listeria monocytogenes.
Phagosomal pH and glass fiber dissolution in cultured nasal epithelial cells and alveolar macrophages: a preliminary study.
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane.
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nrampl) functions as a pH-dependent manganese transporter at the phagosomal membrane.
Production of ROS and NO by NADPH oxidase and nitric oxide synthase, in which both enzymes are generated from NADPH through pentose phosphate pathway [92], and Nox2 negatively regulates the phagosomal proteolysis [93].
We will use genome wide screens and conditional KO mice, associated to quantitative assays for phagosomal functions and cross presentation, to investigate the molecular mechanisms of cross presentation in vitro and in vivo.