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Legionella is another intracellular pathogen that is well adapted to life inside phagosome (Amer et al.
Flotillin-1- enriched lipid raft domains accumulate on maturing phagosomes.
Yoo, "Modulation of macrophage activities in proliferation, lysosome, and phagosome by the nonspecific immunostimulator, mica," PLoS ONE, vol.
Kettle, "Redox reactions and microbial killing in the neutrophil phagosome," Antioxidants & Redox Signaling, vol.
2015), since no phagosomes were detected in the ectoderm.
We will study cross presentation and phagosome functions in primary human DC subpopulations and its regulation by innate receptors for the development of original immunomodulation and vaccination strategies.
that is picked up by receptor-mediated endocytosis in cells: They are enveloped in a lipid-bound container (vesicle, phagosome, then transforming into an endosome or lysosome during transport) and carried actively by transporter molecules along train-tracks (microtubules) that direct them toward the cell nucleus.
Macrophages phagocytize extraneous materials to produce phagosome and then scavenge those extraneous matters by using some enzymes including acid phosphatase.
The NRAMP1 protein is targeted to the membrane of the microbe-containing phagosome, where it may modify the intraphagosomal milieu to affect microbial replication (Canonne-Hergaux et al.
Entosis is a form of cell death in which one cell engulfs one of its live neighbors, which then dies within the phagosome.
4), (16) Adherence of opsonised pathogens to neutrophils and monocytes/macrophages initiates the process of internalisation, resulting in the entrapment of the pathogen in a membranebound, cytoplasmic structure known as the phagosome.
Rhodococcus equi virulence-Associated Protein A is required for diversion of phagosome biogenesis but not for cytotoxicity.
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