pharmacodynamics

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Related to pharmacodynamic: pharmacokinetic

pharmacodynamics

[¦fär·mə·kō·dī′nam·iks]

(pharmacology)

The science that deals with the actions of drugs.

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References in periodicals archive ?

On the basis of mechanism DDIs are divided into pharmacokinetic and pharmacodynamic drug-drug interactions.

Potential Drug-Drug Interactions among patient's prescriptions collected from Medicine out-patient setting

Pharmacodynamic pDDIs were further classified as: (a) synergistic or (b) antagonistic.

Study of potential drug-drug interaction between prescribed drugs in patients attending outpatient department of medicine at tertiary-care hospital in south Gujarat region

A key study that informed our recommendations was conducted by Garonzik et al., [17] who integrated population pharmacokinetic data with pharmacodynamic data in a model to estimate dosing in critically ill patients with a wide range of renal function (including those receiving renal replacement therapy).

Systematic review of the evidence for rational dosing of colistin

M's case, a pharmacodynamic drug-drug interaction among citalopram, aspirin, and clopidogrel caused a GI bleed.

Antidepressants in geriatric patients: reduce the risk of GI bleeding

This study investigated the possible pharmacokinetic and/or pharmacodynamic interaction of echinacea and policosanol with warfarin, in healthy subjects with a known CYP2C9 and VKORC1 genotype.

Echinacea policosanol and warfarin

Therefore, it is important to predict the probabilities that biapenem regimens attain the pharmacodynamic target (30% T > MIC)3 in PF against bacterial populations using a stochastic simulation, in order to rationalize and optimize the regimen for intra-abdominal infections.

Penetrability of intravenous biapenem into the peritoneal fluid of laparotomy patients and the peritoneal pharmacodynamics against gram-negative bacteria

"Platelet function tests suggest there is a pharmacodynamic interaction between 400 mg of ibuprofen and low-dose aspirin when they are dosed concomitantly," the FDA said in a paper posted on its Med-Watch site on Sept.

Alert issued on low-dose aspirin + ibuprofen

High cure rates are possible with high-dose, short-course therapy when a potent, rapidly acting antibacterial agent is used, and pharmacodynamic principles are applied.

Improve antibiotic compliance with short course

Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae for which telithromycin MICs vary.

Telithromycin-resistant Streptococcus pneumoniae

* Drugs or substances modifying pharmacodynamic response (e.g., alcohol, sedatives)

An overview of the drug development process

Pharmacodynamic and pharmacokinetic effects in gingival cervical fluid from redosing during the brushing cycle using an integrated power toothbrush/toothpaste dispensing system.