pharmacodynamics

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pharmacodynamics

[¦fär·mə·kō·dī′nam·iks]
(pharmacology)
The science that deals with the actions of drugs.
References in periodicals archive ?
Quantification of p70S6K phosphorylation may play an adjunct role to pharmacodynamically guide an individualized sirolimus based on immunosuppression.
Lastly, while the breakpoints for many antibiotics, including the carbapenems, are being reduced in an attempt to provide more concordance with clinical success, this will result in a higher proportion of non-susceptible organisms and inadvertent drive clinicians away from pharmacodynamically sound regimens.
The secondary objectives were to evaluate the relationship between the plasma concentration of omecamtiv mecarbil and its echocardiographic effects and to define a range of pharmacodynamically active, well tolerated target plasma concentrations for subsequent clinical trials.
Because hawthorn is readily available without prescription and is indicated for treating congestive heart failure, a person receiving digoxin for heart failure may also be taking hawthorn, which may interact pharmacodynamically with digoxin.
NMP enhanced the permeation of anti-inflammatory drugs like ketoprofen through mouse skin (17) and produced satisfactory analgesic and antiphlogistic effects pharmacodynamically, suggesting effective blood levels of ibuprofen had been reached (18).
Approval of the follow-on product was based on information indicating that the manufacturing process for the follow-on and original product was sufficiently similar; demonstrate structural similarity; were pharmacokinetically and pharmacodynamically similar; and have a similar clinical safety profile.