Pharmacognosy

(redirected from pharmacognosist)
Also found in: Dictionary, Medical.
Related to pharmacognosist: pharmacognosy

pharmacognosy

[‚fär·mə′käg·nə·sē]
(pharmacology)
A subfield of pharmacology which studies the biological and chemical components of medically useful substances that occur naturally (primarily those synthesized by plants).

Pharmacognosy

 

a branch of pharmacy that studies medicinal raw materials of plant and animal origin and various products derived directly from these materials (such as essential and fatty oils, resins, and latex).

The principal concerns of modern pharmacognosy are the investigation of medicinal raw materials, the development of methods for determining the active substances in the materials (including methods involving fluorescence and thin-layer chromatography), and the location of the substances in the various plant and animal organs and tissues in which they concentrate. In addition, pharmacognosy develops methods of discovering wild medicinal plants and performs a number of important functions relating to the standardization of medicinal raw materials. For example, it establishes procedures to be used in collecting, drying, and sorting the raw materials, formulates rules governing the transfer of raw materials to factories and warehouses and the delivery and storage of the materials at these facilities, and sets standards for determining the genuineness and quality of the materials.

Pharmacognosy is the oldest branch of pharmacy. Many medicinal plants were known to the ancient peoples of Southeast Asia and the Middle East. The Greek physician Dioscorides (first century A.D.) is considered the founder of pharmacognosy in Europe. His book Materia medica was used as a handbook on the subject up to the 19th century. Galen and Paracelsus developed new areas in pharmacognosy. Medieval Arab physicians made a major contribution to the field. Original works on pharmacognosy, such as prescription manuals and handbooks for the use of medicinal plants, appeared in Russia in the late 17th and early 18th centuries. The first Russian pharmacopoeia, Pharmacopoea Rossica, came out in 1778; N. M. Ambodik-Maksimovich’s multivolume Materia medica, published between 1783 and 1788, included descriptions of many medicinal plants. A. P. Neliubin, Iu. K. Trapp, and V. A. Tikhomirov also made important contributions to Russian pharmacognosy.

The trend toward specialization in modern pharmacognosy has given rise to the development of pharmaceutical chemistry, the field of drug forms, and biological pharmacy as independent theoretical and practical disciplines. Pharmacognosy is closely associated with such other fields as botany (plant anatomy, management of botanical resources), analytical chemistry, and chemical technology. In the USSR, medicinal raw materials have been standardized by the government since 1926. Problems of pharmacognosy are investigated at the All-Union Scientific Research Institute of Medicinal Plants in Moscow Oblast, the Kharkov Scientific Research Institute of Pharmaceutical Chemistry, and the Institute of Pharmacochemistry of the Georgian SSR and in pharmacognosy subdepartments of pharmacy institutes and other scientific establishments. In the Soviet educational system pharmacognosy is a division of pharmacy and is taught in higher and secondary educational institutions of pharmacy.

REFERENCES

Gammerman, A. F. Kurs farmakognozii, 6th ed. Leningrad, 1967.
Dragendorf, G. Die Heilpflanzen der verschiedenen Völker und Zeiten. Stuttgart, 1898.
Handbuch der Pharmakognosie, 2nd ed., vols. 1–3. Edited by A. Tschirch. Leipzig, 1930–33.

V. V. CHURIUKANOV

References in periodicals archive ?
The American Herbal Products Association (AHPA), Silver Spring, MD, has appointed Holly Johnson, PhD, a pharmacognosist with more than 20 years of industry experience, as its new chief science officer.
That tweaking, noted Steven Dentali, PhD, a pharmacognosist and research fellow in botanical development at global nutrition company Herbalife, typically takes a couple of years, during which labs use the method and report back to AOAC's experts on whether there are details that might need to be improved.
Priority ingredients are picked on the basis of such factors as market importance, adulteration risk, attention from ongoing clinical trials and toxicological concerns, said Steven Dentali, PhD, a pharmacognosist and research fellow, Botanical Development, at Herbalife International, who also sits on the advisory panel.
by Professor D-G Wan, a pharmacognosist, from The Pharmacy Faculty of Chengdu University of Traditional Chinese Medicine (Chengdu, China).
"If you're going to sell fertilizer based on nitrogen content and you have different labs giving different numbers, it makes it hard to do business," said Steven Dentali, PhD, a pharmacognosist and research fellow, Botanical Development, at Herbalife International.
There are also distinctive histochemical features for the trained pharmacognosist, but preference must be given to the certainty of thin-layer chromatographic fingerprint analysis.
Duke, PhD, and the late distinguished pharmacognosist Norman R.
Renowned pharmacognosist and internationally respected medicinal plant re-search expert, Norman Farnsworth, PhD, died at the age of 81 on September 10 at a Chicago hospital.
Kalman raised some interesting and thought-provoking points about regulator and philosophical issues surrounding supplement science, but I won't talk about any of those here because this column is called "Quality Focus" and I am a pharmacognosist, and not a clinical researcher or regulator.
Experts at ConsumerLab.com, such as pharmacognosist William Obermeyer, PhD, calculated the amount of "active" isoflavones in each product, making it possible for consumers to compare products to one another and to clinical standards.
Don is a pantropical plant widely studied by pharmacognosists that contains about 130 terpenoid indole alkaloids (van Der Heijden et al.
However, to accomplish the task of developing drugs and other pharmaceutical medications from these plants, the collaborative effort of botanists, epidemiologist, pharmacognosists, pharmacologists, physicians, and traditional healers must be encouraged at official level (Bannerman, 1982; Brew-Graves, 1977).