Type of medication N (%) Mean (SD) (b) Phenobarbitone
91 (52) 77.89 (20.68) Carbamazepine 15 (8.6) 83.54 (20.55) Phenobarbitone
and valproate 23 (13.1) 71.12 (19.99) Phenobarbitone
and carbamazepine 19 (10.9) 75.09 (24.06) Others 27 (15.4) 83 (18.89) Total (a) 175 (100) 77.97 (20.78) (a) Phenytoin, valproate, combination of phenytoin and valproate, and combination of CZP and phenytoin; (b) p value < 0.238 (not significant).
Effects of cadmium, lead and mercury on induction of hepatic microsomal drug metabolizing enzymes by phenobarbitone
. Zhonggno Yao Lixue Yu Dulixue Zuzhi, 2: 61-65.
Because not all patients on phenytoin or phenobarbitone
develop gingival overgrowth, identifying patients at risk is important in order to take necessary measures to minimize the onset and severity of this condition.
While the phenobarbitone
induced sleeping time test is commonly employed for the assessment of hypnotic properties.
Codeine falls within Schedule III & phenobarbitone
within Schedule IV.
Phenobarbital (previously known as phenobarbitone
in the UK) belongs to a group of medicines called barbiturates.
Oxcarbazepine and carbomazepine had higher risk than phenytoin or phenobarbitone
. Lamotrigine had the lowest risk, but the numbers were small for LTG and other newer antiepileptic drugs.
The antiepileptic drugs such as phenobarbitone
, phenytoin and carbamazepine are known to produce cognitive deterioration as a side effect (66).
In 2008, police for the first time seized 50 kilograms of phenobarbitone
in transit to Pakistan and 800 grams of methamphetamine in transit to Iran.
sodium was obtained from Universal Pharmaceutical Lab.
He explained that following this and other experiments, a drop of broad bean concentrate was examined by a form of chemical analysis (chromatography) and compared with drops of phenobarbitone
(anticonvulsant drug), valium and glycine substance.
However, advances in medication in the 20th century - particularly the discovery of phenobarbitone
in the 1920s - meant it was largely ignored for more than 100 years.