Other tests look for carcinoembryonic antigens and phosphohexose isomerase
(an enzyme implicated in metastasis).
Purification and characterization of phosphohexose isomerase
from human gastrointestinal carcinoma and its potential relationship to neuroleukin.
Of the enzyme systems initially assayed, alcohol dehydrogenase (ADH); lactate dehydrogenase (LDH); malate dehydrogenase (MDH); phosphohexose isomerase
(PHI/PGI); and 6-phosphogluconate dehydrogenase (6-PGD) resolved consistently.
Electrophoretic analysis was successfully performed for nine enzyme systems: isocitrate dehydrogenase, malate dehydrogenase, malic enzyme, acid phosphatase, hexokinase, mannose-phosphate-isomerase, phosphohexose isomerase
, phosphoglucomutase, and [Alpha]-glycerophosphate dehydrogenase, (Table 4).