The need for Group IIA secretory phospholipase A2
([sPLA.sub.2]-IIA) inhibitors in inflammatory ocular disease treatment.
Lipoprotein-associated phospholipase A2
as a novel risk marker for cardiovascular disease: a systematic review of the literature.
Quercetin as an inhibitor of snake venom secretory phospholipase A2
. Chem Biol Interac 2011; 189: 9-16, doi: 10.1016/j.cbi.2010.10.016.
Is lipoprotein-associated phospholipase A2
activity correlated with fibrous-cap thickness and plaque volume in patients with acute coronary syndrome?
(13.) Leandro LF, Mendes CA, Casemiro LA, Vinholis AH, Cunha WR, de Almeida R, Martins CH.Antimicrobial activity of apitoxin, melittin and phospholipase A2
of honey bee (Apismellifera) venom against oral pathogens.
This study aimed to investigate, through molecular docking, affinity interaction of various natural phenolic compounds and some of their derivatives with phospholipase A2
, and see how this interaction occurs in order to contribute to the development of new drugs with anti-inflammatory potential.
Lipoprotein-Associated Phospholipase A2
Activity Is Associated With Riskof Coronary Heart Disease and Ischemic Stroke.
Bickler, "Varespladib (LY315920) appears to be a potent, broad-spectrum, inhibitor of snake venom phospholipase A2
and a possible pre-referral treatment for envenomation," Toxins, vol.
Tselepis, "The role of lipoprotein-associated phospholipase A2
in atherosclerosis may depend on its lipoprotein carrier in plasma," Biochimica et Biophysica Acta, vol.
Leslie, "Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2
," The Journal of Biological Chemistry, vol.
Turmeric, an orange-yellow spice, widely used in curries and South Asian cuisine, is believed to reduce inflammation caused by the enzyme phospholipase A2
, which is provoked into action by pollen in your system.
It has a low molecular weight (2.85kDa) representing about 40-50% of apitoxin dry weight (GAJSKI et al., 2013; YILMAZ et al., 2016), where it synergistically acts with phospholipase A2
(molecular weight 11kDa) which represents 11% of apitoxin dry weight (FERREIRA JUNIOR et al., 2010).