The report provides comprehensive information on the Alkaline Phosphatase (ALKP or Phosphomonoesterase
or Glycerophosphatase or Alkaline Phosphohydrolase or EC 184.108.40.206), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Urease, L-glutaminase, L-asparaginase, alkaline phosphomonoesterase
, and arylsulfatase activities were determined in the rhizospheric soil according to the protocols described by Tabatabai [16, 17].
Phosphatases are classified in different groups, including phosphomonoesterases
which have been extensively studied in soil litter (Turner et al.
Among the soil phosphatases, phosphomonoesterases
and to lesser extent phosphodiesterases, have been the most widely studied.
Acid and alkaline phosphomonoesterase
activity with the substrate p-nitrophenyl phosphate.
Chapuis-Lardy L, Brossard M, Quiquampoix H (2001) Assessing organic phosphorus status of Cerrado oxisols using 31P NMR spectroscopy and phosphomonoesterase
Changes in microbial biomass C, ATP content, soil phosphomonoesterase
and phosphodiesterase activity following air-drying of soils.
Mechanism of action of non specific phosphomonoesterase
Colvan SR, Syers JK, O'Donnell AG (2001) Effect of long-term fertiliser use on acid and alkaline phosphomonoesterase
and phosphodiesterase activities in managed grassland.
Assessing organic phosphorus status of Cerrado oxisols (Brazil) using [sup.31]P-NMR spectroscopy and phosphomonoesterase
Organic acids were found to increase the activity of acid phosphomonoesterase
in soil at low concentrations (<1 [micro]mol/g), whereas higher concentrations (>5 [micro]mol/g) of citric, oxalic, malic, and tartaric acid inhibited this activity .
activity was determined according to the method of Tabatabai and Bremner (1969), with minor modification.