Recently, antibiotics impregnated hydroxyapatite which was prepared by a novel low temperature phosphorization route was developed for bone infection treatment by providing local, sustained, and high concentration ofantimicrobial agents while also function as a restorable bone graft for new bone formation in the injured area [1, 2].
Recently, we successfully applied a low temperature phosphorization process to in situ load nanosilver phosphate into hydroxyapatite structure in a single step which enhances its antibacterial property .
The fabricated 3DP beads were then immersed in the solution and kept at 80[degrees] C for 24 hours to transform to nanosilver phosphate-doped hydroxyapatite by low temperature phosphorization reaction.
A combination of a three dimensional printing technique and low temperature phosphorization process was previously shown to provide a simple mean to direct fabricate low crystalline nanostructure hydroxyapatite which is close to those of bone [21, 22].
Scott said that the study also substantiated that several reactions can take place at the mold-metal interface, including: surface oxidation with consequent burn-on or penetration; carburization/decarburization, including removal of both graphite and carbon from austentite that otherwise would produce pearlite; and sulfurization and phosphorization
of the casting surface when these elements were present in the binder.