Exhaustion

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Exhaustion

 

a state characterized by a lowered level of the functioning of organs, systems, and the body as a whole because of prolonged excessive activity, continuous exposure to powerful stimuli, and certain diseases. The performance of any function is accompanied by intensified decomposition of adenosine triphosphoric acid (ATP) through the utilization of energy accumulated in its terminal phosphate bonds. When ATP formation chronically lags behind its consumption, a precondition for exhaustion is created. The functional elements of organs and systems wear out as they work. The restoration of worn-out structures (functional, energy-forming, and so forth) is based on the synthesis of nucleic acids and proteins. Exhaustion also results if these substances are not synthesized in adequate quantities. The processes of energy formation and protein synthesis are interrelated. The impairment of either may complicate the action of the other and intensify the exhaustion.

Exhaustion may result from extreme fatigue, or slight fatigue after improper or insufficient nutrition, after prolonged exposure to high or low temperatures, after diseases caused by metabolic disorders, and after severe blood losses and injuries. Treatment consists in removing the main causes.

References in periodicals archive ?
In this study, patients more frequently reported greater mental or physical exhaustion and physical disorders before the onset of ISSHL than at the follow-up visit.
Recurrences most often occurred in the setting of febrile viral illness, physical exhaustion, or emotional stress.
Now he is suffering from extreme fatigue, mental and physical exhaustion."
The four subscales are: (1) Positive Engagement (Enthusiastic, Happy, Upbeat); (2) Revitalisation (Refreshed, Energetic, Revived); (3) Tranquillity (Calm, Relaxed, Peaceful); and (4) Physical Exhaustion (Fatigued, Tired, Worn Out).
Physical exhaustion works in a more complicated manner.
Tait, who returned to action earlier this year after taking a break with mental and physical exhaustion in 2008, has played 22 one-day internationals as well as three Tests for Australia.
A study in the March issue of the Journal of Applied Physiology found that people who performed a mentally tiresome task just before exercising reached physical exhaustion much faster than those who were mentally rested before starting their workouts.
He is also concerned with what 'going on crusade' actually involved in addition to lighting: the home-sickness, physical exhaustion, hunger, illness and problems of returning home were just some of the difficulties people faced.
The singer suffered a rumoured breakdown in 2001, when she was admitted to hospital with emotional and physical exhaustion. Earlier this year, she shocked friends and family when she married rapper Nick Cannon following a whirlwind romance.
SYDNEY: Shaun Tait became the latest high-profile Australian to quit cricket yesterday after the fast bowler announced he was taking an indefinite break due to emotional and physical exhaustion.
* Emotional and physical exhaustion (odd shift s, double shift s and overtime expected)