dependence

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Related to physiological dependence: psychological dependence

dependence

[di′pen·dəns]
(medicine)
Habituation to, abuse of, or addiction to a substance.
(statistics)
The existence of a relationship between frequencies obtained from two parts of an experiment which does not arise from the direct influence of the result of the first part on the chances of the second part but indirectly from the fact that both parts are subject to influences from a common outside factor.
References in periodicals archive ?
Most importantly, all major repeaters displayed tolerance symptoms (Criterion 1), and there were very significant ORs for physiological dependence on SB, 66.
Therefore physiological dependence continues to operate as a way of maintaining the status of addiction as a distinct and valid clinical disorder, a disorder that has an extra pathological dimension in addition to patterns of persistent and harmful drug use.
Using a robust behavioral model of physiological dependence, Buck and colleagues (1997) identified a QTL on chromosome 4 that accounts for up to 26 percent of the genetic variance in withdrawal-associated convulsions following acute and chronic ethanol exposure in mice.
Alcohol dependence can be broadly divided into physiological dependence and psychological dependence.
Apart from the physiological dependence on nicotine, there is also a significant psychological dependence that must be addressed in order to achieve a successful and sustained outcome to smoking cessation.

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