(2014) First report of
piebaldism in scolecophidians: a case of Typhlops vermicularis (Squamata: Typhlopidae).
The healthy controls were excluded if they had received blood transfusions in the last 6 months or if they had other autoimmune diseases or other depigmentation disorders, such as
piebaldism and albinism.
[5.] Fontanesi L, Scotti E, Russo V Haplotype variability in the bovine MITF gene and association with
piebaldism in Holstein and Simmental cattle breeds.
A clinical example of this signaling pathway is seen in patients with
piebaldism, which is an autosomal dominant disorder resulting from a mutation in KIT protooncogene leading to the absence of melanocytes and the appearance of leukoderma on the affected areas [16].
For instance, KIT mutations cause dominant white spotting (KITW) in mice and
piebaldism in humans, which both display strikingly similar white patches of hair and skin in heterozygous individuals (Ezoe et al., 1995; Geissler et al., 1988).
Waardenburg syndrome is a rare autosomal disorder with heterogeneous manifestations including sensorineural deafness,
piebaldism, heterochromic irides, synophrys and dystopia canthorum.
Piebaldism involves a lack of pigmentation (Abreu et al.
The epidermal harvesting was initially developed for pigment problems, such as
piebaldism. (Dermatol Surg.
[6] reported a patient with KIT haploinsufficiency and absence of
piebaldism which suggests that the role of KIT is not necessarily a simple dosage effect.
They first isolated melanocytes from the normally pigmented skin of the patient with
piebaldism and then expanded these normal melanocytes in culture, followed by transplanting them into the hypopigmented skin area of this patient.
We diagnosed the newborn with
piebaldism based on her appearance.