plasmacyte


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

plasmacyte

[′plaz·mə‚sīt]
(histology)
A fairly large, generally ovoid cell with a small, eccentrically placed nucleus; the chromatin material is adherent to the nuclear membrane and the cytoplasm is agranular and deeply basophilic everywhere except for a clear area adjacent to the nucleus in the area of the cytocentrum. Also known as plasma cell.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
Mentioned in ?
References in periodicals archive ?
Interstitial tissues were infiltrated with large numbers of lymphocytes and plasmacytes. Immunostaining indicated diffuse infiltration of IgG4 (+) plasma cells.
Clinical symptoms of type I allergic responses are due to a small group of plasmacytes that secrete IgE antibodies, which bind to high-affinity FceRI receptors on basophils and mast cells, and these cells become sensitized.
FNAC of the swelling showed many epitheloid granulomas in a necroinflammatory and caseous background showing polymorphs, histiocytes and few lymph plasmacytes. Special stain for AFB [Fig 6] showed fast staining bacilli ultimately confirming the diagnosis of tuberculous lymphadenitis (cold abscess).
A very scant stroma with inflammatory infiltration consisted of lymphocytes and plasmacytes was observed.
The polyclonal infiltrating plasmacytes are in majority IgG4 positive.
Bronchiolar walls were moderately infiltrated by neutrophils and had multifocal epithelial necrosis and multifocal peribronchiolar moderate infiltration by macrophages and lymphocytes and few neutrophils and plasmacytes. Bronchial lumina harbored few neutrophils and scant edema, fibrin, and cellular debris.
(94,95) This is likely because p38 MAPK inhibition leads to inhibiting IL-6 secretion induced by adherence of malignant plasmacytes to bone marrow stromal cells, a major molecule for the survival and proliferation of myeloma cells.

Full browser ?