Given the clinical symptoms of involuntary muscle activity in the form of fasciculations, muscle aches, cramps and muscle discomfort along with the findings of repeated discharges with doublets and triplets on electromyography and complete resolution of symptoms by steroids and plasmapheresis
we believe our patient was a case of peripheral nerve hyperexcitability and in particular Isaac syndrome.
is the removal, treatment, and return of (components of) blood plasma from blood circulation.
In the literature survey, four case reports (13-15) showed that plasmapheresis
was used to treat hyperthyroidism with hydatidiform mole.
Treatment of myasthenic crisis is very cost effective as it requires ventilator support, IVIG, plasmapheresis
, technical expertise and skilled nursing care.
is usually used in the treatment of AP secondary to hypertriglyceridemia along with insulin and low molecular weight heparin (11).
Although there are no set guidelines for timing of initiation of TPE, there is some evidence from small studies and case reports that early initiation of plasmapheresis
within 48 hours of presentation results in improved morbidity and mortality.
. While approximately 60% of respondents stated their induction choice would differ in a RPGN (Scenario B) or pulmonary hemorrhage (Scenario C) presentation versus Scenario A, there were similarities in the proportions of Rituximab and Cyclophosphamide selections with no difference by specialty.
Evidence on Plasmapheresis
for Patients with Leptospirosis Pulmonary Hemorrhage (Table 1).
Gilson, "Thyroid storm treatment with blood exchange and plasmapheresis
," Journal of the American Medical Association, vol.
Marked reticulocytosis (14.5%) was found in our patient on the eighth day of immunosuppressive treatment and on the fourth day after plasmapheresis
. It was thought that the reticulocyte count might have increased because both antibody production was reduced and immune-mediated destruction of erythrocyte precursor cells in the bone marrow was reduced by way of removal of antibodies that were present in the circulation.
Toxic epidermal necrolysis (TEN), plasmapheresis
, SCORTEN Score.
To date, plasmapheresis
(PPH) together with the application of intravenous immunoglobulins (IVIG) has been the mainstay of ABMR treatment [4, 5].