plasmin


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Related to plasmin: plasminogen, fibrinogen

plasmin

[′plaz·mən]
(biochemistry)
A proteolytic enzyme in plasma which can digest many proteins through the process of hydrolysis. Also known as fibrinolysin.
References in periodicals archive ?
In order for plasminogen to be converted to plasmin, it must first undergo a dramatic change in shape and "open" itself up.
Cell-surface plasmin activity assay was conducted as per standard protocol (Stephens et al.
The resultant plasminogen-streptokinase complex generates plasmin activity that reacts with a synthetic chromogenic substrate.
Alksne JF, Branson PJ, Bailey M: Modification of experimental post-subarachnoid hemorrhage vasculopathy with intracisternal plasmin.
Plasmin breaks down fibrin to x fragments, then further to y
The proteolytic activity of plasmin in dissolving fibrin clots enables pathogens to migrate faster through extracellular matrices (37), and [alpha]-enolase expedites invasion through the host tissues (38) and, ultimately, into the circulatory system.
According to Xanodyne, the drug "acts as a competitive plasmin inhibitor to prevent fibrinolysis by binding to the lysine receptor sites of plasminogen.
Textilinin is a novel recombinant peptide that inhibits plasmin, a key enzyme in the fibrinolytic pathway and has potential to reduce blood loss in major surgery.
The plasmin system is also present in milk but to date no investigation has been undertaken to determine if this enzyme can produce angiostatin.
Structure of an anti-plasmin inhibitor, eckol, isolated from the brown alga ecklonia kurome okamura and inhibitory activities of its derivatives on plasmin inhibitors.
The main function of the fibrinolytic system is to dissolve fibrin clots in the circulation, composed of the inactive precursor plasminogen (Plg) which can be converted into the proteolytic enzyme plasmin by the plasminogen activators (PAs), tissue-type PA (t-PA), and urokinase-type PA (u-PA) (Wun and Capuano, 1985).
Q Periodically a patient has a negative rapid plasmin reagin (RPR) test and a positive absorbed fluorescent treponemal antibody (FTA-ABS) test result.