plasmin


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Related to plasmin: plasminogen, fibrinogen

plasmin

[′plaz·mən]
(biochemistry)
A proteolytic enzyme in plasma which can digest many proteins through the process of hydrolysis. Also known as fibrinolysin.
References in periodicals archive ?
However, it is necessary the release of plasminogen for the fibrinolysis and the release of plasmin is offset by an inhibitor that activates the inflammatory process (22).
Primary fibrinolysis or fibrinogenolysis involves increased fibrinolytic activity because of the imbalance between plasmin and antiplasmins in favour of the former.
5),(38) Another natural inhibitor, aprotinin, trypsin and plasmin inhibitor purified from bovine lungs, also efficiently inhibits HA cleavage and viral multiplication.
Effects of somatic cell count and stage of lactation on the plasmin activity and cheese-making properties of ewe milk.
5) It binds directly to the active site on plasmin, inhibiting its enzymatic function.
The lack of exon 5 in VEGF-111 makes the isoform resistant to plasmin and matrix metalloproteinase, the feature that may be presented as a novel therapeutic property for treatment of ischemic diseases (20).
This decrease was due to the rise in SC as a result of inflammation which reduces the synthesis of the different milk components and also due to increased vascular permeability, causing an abnormal increase in blood plasma containing enzymes such as proteases, lipase and plasmin, that accelerate the breakdown of protein and milk fat [20, 26,29].
Other global assays currently under investigation include clot waveform analysis (4) and simultaneous thrombin and plasmin generation in platelet-poor plasma (5).
This is thought to be due to high levels of plasminogen activator inhibitor -1, which inhibit the formation of fibrinolytic plasmin from plasminogen.
Tranexamic acid prevents clot lysis by occupying the lysine-binding site on plasminogen, activated plasmin, and prevents plasminogen and plasmin from binding to fibrin, which is necessary for clot lysis.
6 Troponin I, ng/mL ND ND Coagulation Prothrombin time, s ND ND International normalized ratio, s ND ND Partial thromboplastin time, s ND ND Dimerized plasmin fragment, ng/mL ND ND Patient value, day of hospitalization ([dagger]) Test 4 5 Hematologic White blood cell count, x [10.
2] plasmin inhibitor acts by reducing the binding of plasminogen to cross-linked fibrin and prevents its prompt elimination by the powerful fibrinolytic system.