plasminogen


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Related to plasminogen: tissue plasminogen activator, thrombin, Plasminogen activator inhibitor

plasminogen

[plaz′min·ə·jən]
(biochemistry)
The inert precursor, or zymogen, of plasmin. Also known as profibrinolysin.
References in periodicals archive ?
ProMetic is currently developing its plasminogen therapy for the management of patients with plasminogen deficiency and has received orphan drug designation from both the FDA and EMA.
Torres-Valdivieso MJ, Cobas J, Barrio C, Munoz C, Pascual M, Orbea C, Rodriguez E, Gutierrez E Successful use of tissue plasminogen activator in catheter-related intracardiac thrombus of a premature infant.
Congenital hydrocephalus as a rare association with ligneous conjunctivitis and type I plasminogen deficiency.
Plasminogen activator inhibitor-1 4G4G genotype is associated with myocardial infarction but not with stable coronary artery disease.
We were very surprised to find that a simple sugar tethered to plasminogen guards access to the site of activation," said Dr.
Results from the two-dimensional SDS-PAGE analysis showed the return of the possible plasminogen polymer to the region of the monomeric plasminogen standard, at around a molecular weight of 90,000 Da.
Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases.
An identical effect was seen when plasminogen was mixed with human brain tissue infected with the 'classic' form of CJD.
Similarly, in a cost-effective analysis of thrombolytic therapy with tissue plasminogen activator (t-PA) compared to streptokinase, the authors conclude, "The cost-effectiveness of treatment with accelerated t-PA rather than streptokinase compares favorably with that of other therapies whose added medical benefit for dollars spent is judged by society to be worthwhile.
Angiostatin and endostatin are fragments of two larger proteins, collagen and plasminogen, that occur naturally in the body.
Nash, MD, FAHA, CPI are currently enrolling patients to participate in clinical research trial investigating potential use of a plasminogen activator derived from vampire bats to treat individuals experiencing an acute ischemic stroke.

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