plasminogen


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plasminogen

[plaz′min·ə·jən]
(biochemistry)
The inert precursor, or zymogen, of plasmin. Also known as profibrinolysin.
References in periodicals archive ?
Another gel was analyzed using the Western blot technique under non-reducing conditions using a specific antibody against plasminogen.
Fibrinolysis pathway genes assessed were: tPA, uPA, plasminogen, PAI-1, and fibrinogen.
Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor.
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke.
Currently in the United States, a drug called recombinant tissue plasminogen activator (rt-PA) is approved for treating strokes which have been caused by clots blocking blood flow to the brain.
An identical effect was seen when plasminogen was mixed with human brain tissue infected with the 'classic' form of CJD.
Cost-effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction, N Engl J Med, 1995, 332:1418-24.
Most acute ischemic stroke patients arrive after the 3-hour time window for tissue plasminogen activator (tPA) administration which is currently the only FDA approved treatment for acute ischemic stroke.
TSX: PLI; OTCQX: PFSCF) has received Swedish Medical Products Agency clinical trial application approval to commence a Phase 2 clinical trial of its plasminogen therapy in patients suffering from diabetic foot ulcer (DFU), the company said.
Biopharmaceutical company Prometic Life Sciences Inc (TSX:PLI) (OTCQX:PFSCF) said on Wednesday that it has submitted its plasminogen Biologics License Application (BLA) with the US FDA for the treatment of patients with plasminogen congenital deficiency.

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