pleocytosis


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pleocytosis

[‚plē·ō‚sī′tō·səs]
(medicine)
Increase of cells in the cerebrospinal fluid.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Patients with probable AFM met the clinical criterion and had CSF pleocytosis (>5 white blood cells per cubic mm) (10).
Standard clinical CSF analyses of the patients over time showed lymphocytic pleocytosis (range 11-361 cells/[micro]L, median 142 cells/[micro]L [reference <5/[micro]L]) (Figure 5, panel A), markedly elevated protein concentrations (range 824-6,092 mg/L, median 1,976 mg/L [reference <500 mg/L]) (Figure 5, panel B), lactate level elevation (range 2.9-8.47 mmol/L, median 5.1 mmol/L [reference <2.1 mmol/L]) (Figure 5, panel C), and blood-brain barrier dysfunction.
His brain CT scan was normal, but CSF analysis detected pleocytosis of 15 with 80% polymorphonuclear cells and 20% lymphocyte, glucose 104, and a high protein of 89 mg/dl.
Cerebrospinal fluid analysis showed mild pleocytosis, normal blood brain barrier function, and oligoclonal bands type 3.
The diagnosis of TBM was based clinically on symptoms like fever, headache, altered mental state and signs of meningeal irritation with CSF findings of increased proteins, low glucose and lymphocytic pleocytosis. Lumbar puncture was done and approximately 4ml of CSF sample was withdrawn for analysis.
CSF analysis was insignificant with normal sugar and proteins without pleocytosis except in one patient having lymphocytosis with raised CSF proteins.
Abnormal biochemical values and pleocytosis were present in 63% of patients, representing a substantial number of abnormal specimens.
Typical CSF picture for TBM was defined as lymphocytic pleocytosis (increased number of cells which are predominantly lymphocytes), elevated protein and low CSF glucose concentration.
All four patients had pleocytosis of the CSF, two had elevated levels of proteins in the CSF, and one patient had convulsion.
She also proposed risk features to identify those infected with herpes simplex virus; age less than 42 days, vesicular rash, elevated alanine transaminase (ALT) and aspartate aminotransferase (AST), CSF pleocytosis, and seizure or twitching.
Lack of pleocytosis in the CSF supports the hypothesis that MERS is an infection-associated encephalopathy syndrome rather than an encephalitis.