polycystic ovary syndrome

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polycystic ovary syndrome

a hormonal disorder in which the Graafian follicles in the ovary fail to develop completely so that they are unable to ovulate, remaining as multiple cysts that distend the ovary. The result is infertility, obesity, and hirsutism
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XORTX has two lead programs to develop treatments for progressive kidney disease due to diabetes, diabetic nephropathy and polycystic kidney disease
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, presenting in up to 18% of this population1.
Polycystic Ovary syndrome is a common gynaecological problem affecting 25 percent of general population.
Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorder affecting 5-10% of the women in the reproductive age group.4 Common features of PCOS are seborrhea, acne, hirsutism, acanthosis nigricans, alopecia and if left unrecognized or untreated it can lead to metabolic, reproductive, psychological and neoplastic complications.5 Cutaneous changes are one of the earliest manifestations of PCOS, and as the skin is visible and accessible organ in the body, observation of the former can be of extreme value to the clinician in diagnosing PCOS.
Amenontiea associated with bilateral polycystic ovaries.
Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders with a prevalence of approximately 60-70% in Chinese obese women of reproductive age.[1] The common manifestations of PCOS are oligomenorrhea, chronic anovulation, hyperandrogenism, hyperinsulinemia, and polycystic ovaries on ovarian ultrasonography.[2] PCOS increases the risks of type 2 diabetes, cardiovascular disease, endometrial cancer, and ovarian cancer.[3],[4] The pathogenesis of PCOS remains unclear, although it is considered to be the result of interaction between genetic, environmental, and lifestyle factors.
Since 2003, large amount of literature has been published questioning the Rotterdam criteria of polycystic ovarian morphology and its utility as a marker of PCOS.
For the diagnosis of PCOS, ultrasound can be used to check for polycystic ovaries and endometrial thickness.
M2 EQUITYBITES-April 25, 2018-PKD Foundation wins US FDA approval for JYNARQUE to treat polycystic kidney disease

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