polymyositis


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Related to polymyositis: Polymyalgia rheumatica

polymyositis

[¦päl·i‚mī·ə′sīd·əs]
(medicine)
Inflammation of many muscles simultaneously.
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References in periodicals archive ?
Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis.
The combination of two or more autoimmune entities is a well-known clinical phenomenon, commonly described as poly-autoimmune syndrome and applicable to the present case with polymyositis and autoimmune hepatitis.
anti-CCP IgA-RF IgG-RF IgM-RF Psoriatic arthritis 4 0 (0%) 3 (75%) 4 (100%) 2 (50%) SLE 18 2 (11%) 17 (94%) 9 (50%) 7 (39%) Scleroderma 15 4 (27%) 15 (100%) 14 (93%) 14 (93%) Polymyositis 7 1 (14%) 6 (86%) 7 (100%) 6 (86%) No.
Of these 19 indications, the product currently generates substantially all of its net sales from the following on-label indications: the treatment of proteinuria in the nephrotic syndrome of the idiopathic type (NS), the treatment of acute exacerbations of multiple sclerosis (MS) in adults, the treatment of infantile spasms (IS) in infants and children under two years of age, and the treatment of certain rheumatology related conditions, including the treatment of the rare and closely related neuromuscular disorders dermatomyositis and polymyositis.
Patients with other inflammatory diseases were also reported in decreasing frequency as follows: ITP (n=8), APS (n=5), Sjogren's syndrome (n=5), polymyositis (n=4), Wegener's granulomatosis (n=3), autoimmune hemolytic anemia (AIHA) (n=2), scleroderma (n=2), Still's disease (n=1), dermatomyositis (n=1), pemphigus vulgaris (n=1), bullous pemphigoid (n=1), ankylosing spondylitis (n=1), polyarteritis nodosa (n=1), and sickle cell disease (n=1).
1) Cases of UIP can occur either idiopathically (I-UIP) or in the setting of systemic connective tissue disease (CTD-UIP), such as rheumatoid arthritis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, polymyositis, dermatomyositis, and mixed connective tissue disease.
Inflammatory myopathies have been associated with malignancy but are most frequently seen with dermatomyositis (DM) and polymyositis (PM).
Symptoms of pain and weakness should alert the clinician to consider polymyositis and/or dermatomyositis.
2) Systemic connective tissue disorders that can occur simultaneously with keratitis sicca and xerostomia are rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, polymyositis or mixed connective disease.
Muscle diseases that cause myocyte damage (such as muscular dystrophies, polymyositis, and rhabdomyolysis) and muscle trauma all cause much greater increases in AST than in ALT because of the higher relative activity of AST in skeletal muscle.