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Related to polypeptide: Polypeptide chain


see peptidepeptide,
organic compound composed of amino acids linked together chemically by peptide bonds. The peptide bond always involves a single covalent link between the α-carboxyl (oxygen-bearing carbon) of one amino acid and the amino nitrogen of a second amino acid.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an organic compound containing six to 80–90 amino acid residues; the upper limit corresponds to a molecular weight of about 10,000. Such polypeptides, unlike proteins, can pass through semipermeable membranes.

The simple polypeptides are crystalline substances that are readily soluble in water and have chemical properties similar to those of amino acids. The complex polypeptides are amorphous and react with water to yield colloidal solutions. Polypeptides are formed in the organism during enzymatic proteolysis (autolysis of tissue, digestion, and so on) and during biosynthesis from amino acids. Many natural polypeptides exhibit the biological activity of hormones, antibiotics, and toxins. Synthetic polypeptides serve as models in studying the structure and biological activity of proteins.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


A chain of amino acids linked together by peptide bonds but with a lower molecular weight than a protein; obtained by synthesis, or by partial hydrolysis of protein.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Lonza acquired the Braine peptide business in 2006 from UCB, while PolyPeptide's corporate roots in peptide therapeutics date back to the 1950s.
Table 1: Polypeptide profile of chromium resistant cyanobacterial strains under 0g mL-1 and 50g mL-1 chromium r=reduced expression of polypeptide,d=polypeptide inhibited,m=more expression
Kleijer et al., "Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane," Proceedings of the National Academy of Sciences of the United States of America, vol.
Polypeptides are synthesized on particles called ribosomes.
(1996) visualized a common polypeptide with molecular weight of 43 kDa out of eight proteins in different field isolates.
Elastin-like polypeptides (ELPs) are a class of genetically modified, E.Coli-generated polypeptides that have demonstrated promise as cell culture substrates [2-5].
As can be seen from Figure 2, trypsin adsorbed readily to the polypeptide surface and increased the thickness up to 5 times.
Finally, the polypeptide bands were visualized by the addition of NBT and BCIP when alkaline phosphatase-conjugated antibodies were used, or DAB and hydrogen peroxide when horseradish peroxidase-conjugated antibodies were employed, according to the provider.
bovis (NC 317) separatelybythe previously described method [23] to find out cross-reactive polypeptides.
This reinforces the idea that polypeptide chains have varying lengths and will assess whether students are able to recognize the STOP codon.
Waldispuhl has already tested the model on a polypeptide called protein G, one of the few proteins for which information about the folding pathway is available.
The research team, led by Lars Baltzer at Uppsala University, presented the concept of a tiny polypeptide consisting of 42 amino acids to which virtually any target-seeking organic molecule can be bound.