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Related to polypeptide: Polypeptide chain


see peptidepeptide,
organic compound composed of amino acids linked together chemically by peptide bonds. The peptide bond always involves a single covalent link between the α-carboxyl (oxygen-bearing carbon) of one amino acid and the amino nitrogen of a second amino acid.
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an organic compound containing six to 80–90 amino acid residues; the upper limit corresponds to a molecular weight of about 10,000. Such polypeptides, unlike proteins, can pass through semipermeable membranes.

The simple polypeptides are crystalline substances that are readily soluble in water and have chemical properties similar to those of amino acids. The complex polypeptides are amorphous and react with water to yield colloidal solutions. Polypeptides are formed in the organism during enzymatic proteolysis (autolysis of tissue, digestion, and so on) and during biosynthesis from amino acids. Many natural polypeptides exhibit the biological activity of hormones, antibiotics, and toxins. Synthetic polypeptides serve as models in studying the structure and biological activity of proteins.


A chain of amino acids linked together by peptide bonds but with a lower molecular weight than a protein; obtained by synthesis, or by partial hydrolysis of protein.
References in periodicals archive ?
Sterile HCF of goat revealed only one polypeptide band of 78kDa (log MW 1.
We investigated possible effects of VCP on human cell protein synthesis by examining changes in the polypeptide composition of each human cell type used in time-course experiments of 0-24 hr exposure.
Otsu-shi, Japan) has patented a polypeptide having an activity for targeting a heterogeneous polypeptide to a surface of cytoplasmic membrane, a nucleic acid encoding the polypeptide, a construct for introducing into a cell, comprising the nucleic acid, a transformant harboring a carrier for introducing into a cell, a method for localizing a polypeptide on a cell surface, a method for detecting the polypeptide or nucleic acid and a kit therefor, and a method for detecting a ligand or receptor for the polypeptide.
Isolated polynucleotide and polypeptide sequences are provided, along with an expression vector comprising the isolated polynucleotide, a host cell comprising the isolated polynucleotide, and a transgenic plant comprising the isolated polynucleotide.
Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, Israel) has patented a method of producing a recombinant polypeptide having .
A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interest is also provided.
9738687, is entitled "Polypeptide-based shuttle agents for improving the transduction efficiency of polypeptide cargos to the cytosol of target eukaryotic cells, uses thereof, methods and kits relating to same.