Polyribosome


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polyribosome

[‚päl·i′rī·bə‚sōm]
(cell and molecular biology)

Polyribosome

 

(or polysome), a protein-synthesizing complex in living cells; each complex is composed of one molecule of messenger ribonucleic acid (mRNA) and a few or several ribosomes connected to the mRNA molecule.

Polyribosomes are formed by the successive addition of ribosomes to mRNA. As they pass along the mRNA one by one, the ribosomes “read out” the information contained in the mRNA; it means that each ribosome synthesizes one molecule of protein (polypeptide chain) according to the program recorded in the mRNA. Protein synthesis in the cell is effected primarily by polyribosomes rather than by individual ribosomes.

References in periodicals archive ?
The rates at which [14.sup]C-labeled amino acids were incorporated into nascent peptides (i.e., polyribosome fraction, as in Fig.
Sassone-Corsi, "Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA," Molecular and Cellular Biology, vol.
Fragile-X mental retardation protein (FMRP) is a protein involved in ferrying RNA transcripts to polyribosomes located at sites of protein synthesis.
Common findings were dilated stacks of rough endoplasmic reticulum, polyribosomes, randomly distributed intermediate filaments, and rare collagen secretion granules (Fig 5).
The cytoplasm of endotheliocyte is also differed by extreme enlightenment; there are few polyribosomes in it.
Similar to some data, the current investigation showed that C[Cl.sub.4] toxicity resulted in reduction of liver total protein content in C[Cl.sub.4]-treated rats suggesting the disruption and disassociation of polyribosomes from endoplasmic reticulum following C[Cl.sub.4] administration (Clawson, 1989).
Separation of the messenger RNA of reticulocyte polyribosomes. Biochem Biophys Res Commun 1964; 16: 522-527.
Metabotropic glutamate receptor-initiated translocation of protein kinase p90rsk to polyribosomes: a possible factor regulating synaptic protein synthesis.
Also, the other cellular alterations such as decreased protein content, increased ribonuclease activity, protein hydrolysis, hydrogen peroxide concentration and dissociation of polyribosomes are also known to occur in plants exposed to water stress [15,22].
Contents of DNA, polyribosomes, ribosomal RNA, protein and Chlorophyll.
FMRP associates with polyribosomes as an mRNP, and the 1304N mutation of severe fragile X syndrome abolishes this association.