Danny suffers from diffuse intrinsic pontine
glioma, a disease that kills around 90 per cent of its patients within 18 months of diagnosis.
Chloe was diagnosed with a Diffuse Pontine
Glioma – a tumour on her brain stem – in September 2010.
An MRI of the brain revealed "central pontine
The activity of these burst neurons is controlled by omnipause neurons in the pontine
Definitive tissue diagnosis again is not generally feasible due to the risks associated with pontine
, midbrain, or basal ganglial biopsies.
acute encephalopathy following hyponatraemia, with a pontine
lesion would suggest pontine
myelinolysis (refer to Table 1).
Aggressive treatment of chronic hyponatremia may be associated with an increased risk of osmotic demyelination, which appears to be caused by the shrinkage of the brain, leading to demyelination of pontine
and extrapontine neurons.
Winston Churchill called him the Bullfrog of the Pontine
variable number of signs of a dorsal pontine
One particular physiological event, which is a hallmark sign of REM sleep, is the appearance of phasic pontine
In contrast, clinical manifestations that primarily present as the coexistence of distal renal tubular acidosis and central pontine
myelinolysis (CPM) are very rare in pSS.
Pick bodies were also present in temporal and parietal cortex, caudate and putamen, substantia nigra, locus coeruleus, and pontine
nuclei (not shown).