postencephalitic parkinsonism


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postencephalitic parkinsonism

[‚pōst·in‚sef·ə′lid·ik ′pärk·ən·sə‚niz·əm]
(medicine)
The parkinsonian syndrome occurring as a sequel to lethargic encephalitis within a variable period, from days to many years, after the acute process.
References in periodicals archive ?
* Postencephalitic parkinsonism. Just after the first World War, a viral disease, encephalitis lethargica, attacked almost 5 million people throughout the world, and then suddenly disappeared in the 1920s.
After an outbreak of encephalitis lethargica between 1915 and 1926, a condition of unknown origin with acute onset and often chronic persistence of various neurological symptoms, including headache, lethargy, catatonia, parkinsonism, and tremor, a potential link between an altered mental state and parkinsonism was proposed and the first idea of complex psychotic symptoms in postencephalitic parkinsonism (PEP) cases was described [6, 7].
From the 1920s to the 1950s, the differences between PD and postencephalitic parkinsonism were discussed not only clinically, but also neuropathologically.