Choroiditis

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Related to posterior uveitis: anterior uveitis

choroiditis

[‚kȯr ‚ȯi′dīd·əs]
(medicine)
Inflammation of the choroid.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Choroiditis

 

inflammation of the vascular coat of the eye, usually affecting the retina as well (choroidoretinitis). The most frequent cause of choroiditis is an infectious disease such as tuberculosis or toxoplasmosis. The causative agent of the infection usually penetrates the vascular coat through the bloodstream. Atrophic patches then form at the focal sites of the inflammation. Patients complain of clouded vision and often of decreased visual acuity. Ophthalmoscopy is an effective means of diagnosing choroiditis. Treatment, whether general or local, depends on the cause of the inflammation. Antibiotics may be used in the general form of treatment.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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Infliksimab treatment of posterior uveitis. Ophthalmology 2004; 111: 197-8.
Sight-threatening intermediate and/or posterior uveitis requires treatment.
Both trials will have a primary end-point of recurrence of posterior uveitis at 12 months and are planned to involve about 300 patients in total.
They reported that "ocular syphilis led to the HIV diagnosis in 52% of cases, posterior uveitis was significantly more common in individuals with CD4 cell count < 200 cells/[mm.sup.3], and 97% of patients with visual impairment improved following intravenous penicillin or ceftriaxone." In our analysis, the mean CD4 cell count ranged from 122 to 504 cells/[mm.sup.3], supporting the recommendations that most patients with syphilitic uveitis and HIV coinfection should be treated according to the recommendations for HIV-negative patients (e.g., as immunocompetent patients) and should be monitored closely [1].
The eyes with refractory posterior uveitis not responding to immunosuppressive drugs, associated with dense vitreous opacities interfering with visual potentials, epiretinal membranes with associated cystoids macular edema (CME), or impending traction on the retina, were recruited thereafter for the proposed treatment protocol.
(7,8,12,14) But in a report from Southern Turkey, Soylu15 noticed that anterior and panuveitis had almost the same frequency (33.3%, 34.4%) and in another report by Kadayifcilar, (16) anterior uveitis was the most common form but was followed by posterior uveitis. Also, there are reports notifying that intermediate uveitis was the most common form in their series.
These two Phase III trials are expected to enroll a total of 300 patients, which is in addition to the previous investigator-sponsored trial studying the same device for posterior uveitis, added the company.
In this review we examine FAF patterns in infectious and noninfectious posterior uveitis and discuss the change in these patterns in relation to disease activity.
The first one looked at 30 eyes from 30 Korean patients and compared the subfoveal choroidal thickness in these eyes during the active and quiescent phases of posterior uveitis. Subfoveal choroidal thickness during the acute stage (398.77 [+ or -] 155.59 [micro]m) was significantly greater than the quiescent phase of the disease (356.72 [+ or -] 141.09 [micro]m) and significantly correlated with the amount of leakage on the FFA [22].
There are many causes of posterior uveitis that can give rise to this symptom, for example the systemic inflammatory condition sarcoidosis.
Ophthalmicmanifestations, especially in chronic brucellosis, include posterior uveitis in about 40% of patients and anterior, intermediate, or panuveitis in another 15% each.
The initial clinical impression was that of retinal vasculitis with posterior uveitis (Figure 1).

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