posttranslational modification

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posttranslational modification

[‚pōs·tranz¦lā·shən·əl ‚mäd·ə·fə′kā·shən]
(cell and molecular biology)
Any polypeptide alteration that occurs after synthesis of the chain.
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As with feedback control, posttranslational activation of the protein product of gene G by S may also occur (Figure 3A,D,G; dashed lines).
Of the three classes of epigenetic modifications, posttranslational modification of histone proteins undoubtedly is the most complex.
There are over 300 protein kinase enzymes that control specific posttranslational process through selective phosphorylation.
Early chapters cover the MBP gene, the functions of the golli proteins, and posttranslational modification of MPB.
Alcohol can regulate a membrane-bound ion channel in several ways: by changing the activity of proteins through posttranslational modifications, interacting with membrane lipids, interacting with auxiliary proteins, modulation of membrane protein expression (i.
Among the epigenome which is defined by DNA methylation patterns and the associated posttranslational modifications of histories and non histone proteins is the key regulatory circuit (2).
13) Citrullination is the posttranslational deimination of arginine residues by peptidylarginine deiminase (PAD), which hydrolyzes the [NH.
Posttranslational modifications, extensive technological platforms and sophisticated informatics infrastructure.
In large part, the anti-inflammatory actions of statins result from the depletion of two biologically important cholesterol pathway intermediates, farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP), which are required for posttranslational modification of small GTP-binding proteins (small GTPases) such as Ras (FPP) or Rac and Rho (GGPP) (Figure 3).
Citrullination is a process in which proteins undergo posttranslational conversion of peptidyl-arginine to peptidyl-citrulline.
This discovery of posttranslational modifications in the proximal part of the neuron represents a major paradigm shift, said Bhattacharya.
Objective: Cellular processes are largely governed by sophisticated protein posttranslational modification (PTM)-dependent signaling networks, and a systematic understanding of regulatory PTM-based networks is a key goal in modern biology.

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