Potentiation


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Potentiation

 

an increase in the efficiency of the physiological mechanisms after a period of activity. Potentiation is widespread in nature, but its underlying mechanisms vary from case to case.

An important part in neural activity is played by postsynaptic potentiation, manifested by facilitated transmission of a signal across a synapse for many seconds or several minutes after a period of synaptic activity. Postsynaptic potentiation is based on the increased probability of a mediator’s quanta being released from presynaptic nerve endings and is believed to be one of the mechanisms involved in learning and memory.

Potentiation is also characteristic of muscular activity (contraction potentiation) and of the sensory organs (light and sound potentiation). Here it results from the slowly subsiding effects of afterdischarge.

References in periodicals archive ?
However, in contrast to phenytoin, topiramate appears to enhance contraction by tetanic potentiation.
In contrast to the potentiation of the affected leg, there were statistically significant impairments of contralateral CMJ height suggesting the coexistence of post-activation potentiation (affected limb) and crossover neural fatigue.
Generalizability to Other Epithelioid Human Neuroblastoma Cell Lines ofp75NTR-CRABP1 Coordinate Regulation as a Mechanism for p75NTR-Induced Potentiation of Fenretinide Efficacy.
Intermittent exercise as a conditioning activity to induce postactivation potentiation.
MVC-induced short-term potentiation of explosive force Les MCV engendrant un potentiel de force explosive a court terme La potenciacion a corto plazo de la fuerza explosiva producida por contracciones voluntarias maximales (CVM).
potentiation during anticipation, which might be explained by a number of procedural differences across studies.
Affect potentiation refers to one of the most relevant etiological mechanisms involved in alcohol use and abuse.
Long-term potentiation at C-fibre synapses by low-level presynaptic activity in vivo.
98),(99) They are depolarization-induced suppression of inhibition (DSI)98) and depolarizationinduced potentiation of inhibition (DPI).
The aim of both of these dynamic methods of potentiation is to increase and maximise power generation during the explosive activity.
Both NMDA and AMPA receptors are involved in regulating the synapse plasticity via long-term potentiation (LTP).
Furthermore, n-3 fatty acid deprivation during development resulted in marked decreases of synapsins and glutamate receptor subunits in the hippocampi of 18-day-old pups with concomitant impairment of long-term potentiation, a cellular mechanism underlying learning and memory.