potentiator


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potentiator

[pə′ten·chē‚ād·ər]
(food engineering)
(pharmacology)
A drug that augments the response of a second drug so that the total response is greater than the predictible additive effect.
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RPL554-induced CFTR activity was further increased by the potentiator VX-770, suggesting additional benefit by the drug combination.
The available research indicates that plant polyphenols, in particular those of tea (Camellia sinensis), are potent inhibitors of iron absorption from the GIT, and suggests that in combination with the avoidance of known potentiators of iron uptake (meat, alcohol, fructose and vitamin C) consumption of tea polyphenols may be beneficial in individuals with HH and aid in the management of their condition.
2008), which encodes the macrophage infectivity potentiator, a virulence factor mediating intracellular infection of human macrophages as well as free-living protozoa (Cianciotto & Fields 1992).
One study, which compared the use of papain-treated RBCs to procedures involving LISS alone or LISS-papain combinations, found that the use of a potentiator in adsorption procedures decreased the mean processing time from 180 minutes to 57.
Interleukin-1 is a potent inducer of IL-6, and the combination of IL-1 and IL-6 can act as a megakaryocyte potentiator as well.
is a potentiator for the entire anti-PD-1/PD-L1 drug class.
A potentiator is a drug increasing the reaction of a second drug, so that the targeted effect is greater.
24, 2013 /PRNewswire/ -- Galapagos NV (Euronext: GLPG) and AbbVie (NYSE: ABBV) announced today that they have entered into a global alliance to discover, develop and commercialize novel potentiator and combination therapies in cystic fibrosis (CF), an inherited chronic disease that affects 70,000 people worldwide.
Ramsey of the Seattle Children's Research Institute and colleagues conducted a randomized, double-blind, placebo-controlled trial to evaluateivacaftor (VX-770), a CFTR potentiator, in patients with cystic fibrosis.
Known as a CFTR potentiator, ivacaftor is an oral medicine that aims to help the CFTR protein function more normally once it reaches the cell surface, to help hydrate and clear mucus from the airways.
This revolutionary "toolkit" combines three clean label ingredients from DSM--CakeZyme[TM], ETENIA[TM] and the taste potentiator Delite.