lesion

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Related to precancerous lesion: actinic keratosis

lesion

any structural change in a bodily part resulting from injury or disease
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

lesion

[′lē·zhən]
(biology)
A structural or functional alteration due to injury or disease.
(cell and molecular biology)
A damaged site in a gene, chromosome, or protein molecule.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
An epidemiologic assessment of cancer risk in oral precancerous lesions in India with special reference to nodular leukoplakia.
The economic cost and morbidity associated with over treatment is acceptable and health workers can confidently inform women with positive result that they are very likely to have precancerous lesion of the cervix and go ahead and treat.
Motalleb nezhad and colleagues (17) have studied the knowledge of general dentists about oral cancer examination; participants were asked some questions about the precancerous lesions too.
The fact that the majority of precancerous lesions have been found in women aged 25-49 may be explained by the fact that persistent infection with human papillomavirus (considered to be the main cause of cervical cancer) occurs often in young age.
However, when old cells return to a stem cell-like status, they can carry with them all of the mutations that have accumulated to date, predisposing some of those cells to developing into precancerous lesions.
Many countries are currently considering switching from classic Pap tests to primary HPV tests for cervical cancer screening, based on strong evidence linking cervical abnormalities and infection with certain HPV types and data suggesting that HPV tests detect more high-grade precancerous lesions. However, no study has yet compared the different methods in a population in which younger women had been offered prior HPV vaccination.
Now that the concept, which only costs about $5, has been proven, the team believes it could be applicable to some breast cancers and cervical precancerous lesions.
A Systematic Review of Available Evidence: Efficacy of the Two Vaccines against HPV" [1], there was an error in the Discussion section, where "Our systematic review highlights that, for precancerous lesions (CIN), the only available proxy of cervical cancer and heterogeneity among pooled studies is substantial" should be changed to "Our systematic review highlights that, for precancerous lesions (CIN), the only available proxy of cervical cancer, heterogeneity among pooled studies is substantial."
However, only a few studies detail the frequency of precancerous lesions such as gastric adenomas or gastric cancer in colorectal cancer patients.
Risk factors for cervical cancer are the presence of the human papillomavirus (HPV) or human immunodeficiency virus, a compromised immune system, in utero exposure to diethylstilbestrol (synthetic nonsteroidal used to prevent miscarriage from 1938-71) and/or previous treatments of high-grade precancerous lesions.