pregnanediol


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pregnanediol

[preg‚nan·ə′dī‚ȯl]
(biochemistry)
C21H36O2 A metabolite of progesterone, present in urine during the progestational phase of the menstrual cycle and also during pregnancy.
References in periodicals archive ?
It is not at all unusual to see pregnanediol values for a woman in her mid-late forties well down below the luteal range.
[6] Nonstandard abbreviations: C21OHD, classic 21-hydroxylase deficiency; 17OHP, 17[alpha]-hydroxyprogesterone; POR, cytochrome P450 oxidoreductase; PORD, POR deficiency; TH17OHP, transient hyper 17OHPnemia; Ptl, pregnanetriolone; 21DOF, 21-deoxycortisol; 11HA, 11[beta]-hydroxyandrosterone; PD, pregnanediol; GC-MS-SIM, GC-MS/selected ion monitoring; THE, tetrahydrocortisone; DHEA, dehydroepiandrosterone; AD4, androstenedione; 11OHAD4, 11[beta]-hydroxyandrostenedione.
Levels of urinary pregnanediol, following 100 to 300 mg oral dosing, are much higher than levels seen in women during the luteal phase of the menstrual cycle, which taken at face value could be misconstrued as overdosing.
Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research.
[9] Nonstandard abbreviations: EIA, enzyme immunoassay; E2, estradiol; P4, progesterone; E1C, estrone conjugate; PDG, pregnanediol 3-glucuronide; DRT, days at room temperature; FT, freeze-thaw; and LH, luteinizing hormone.
Steroid hormones, including aldosterone, corticosterone, dehydro-epiandrosterone (DHEA), estrogens, pregnanediol, progesterone, and testosterone, enhance the function of Pramiracetam.
Adrenal Steroid Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Pregnanediol H H H H L 0 Androsterone H H H H L 0 Etiocholalone H H H N N 0 DHEA H H N L N 0 Pregnanetriol H H N L N 0 11-Ketoandrosterone H H N L N 0 11-ketoetiocholalone H N L L L 0 11-OH-androsterone H L L N L 0 * Case 1:54-yr-old woman hypertension, diverticulitis, palpitations, and severe Katribarelated stress.
Validations of time-resolved fluoroimmunoassays for urinary estrone 3-glucuronide and pregnanediol 3-glucuronide.
According to the 1999 edition of Tietz' Textbook of Clinical Chemistry, "Urinary assays are considered to reflect the secretory activity of the endocrine glands." (10) The textbook also states that "urinary free cortisol and the measurement of urinary free estradiol, estrone, and testosterone have been shown to provide clinical information that can reflect the production rates of these steroids."10 Moreover, 24-hour urine testing for pregnanediol (progesterone metabolite) is the best biochemical assessment of ovulation based on progesterone production.
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