pk

(redirected from Prekallikrein)
Also found in: Dictionary, Thesaurus, Medical, Financial.
Related to Prekallikrein: High molecular weight kininogen

pk

(mechanics)
peck

pK

(chemistry)
The logarithm (to base 10) of the reciprocal of the equilibrium constant for a specified reaction under specified conditions.

PK

(psychology)
psychokinesis

pk

(networking)
The country code for Pakistan.
Mentioned in ?
References in periodicals archive ?
The rationale for the assay is that a contact activator is used to provide a surface for high-molecular-weight kininogen, prekallikrein, and FXII, thereby stimulating the production of FXIIa.
Thromboelastography in selected avian species
During pre-incubation time, contact factors (XII and XI) are activated in the presence of high molecular weight kininogen and prekallikrein. The activated factor XI, converts factor IX to [IX.sub.a].
Clinical and laboratory approaches to hemophilia A
Activated FXII (FXIIa) then cleaves prekallikrein (complexed to the cofactor HK), generating PKa.
Ecotin-like ISP of L. major promastigotes fine-tunes macrophage phagocytosis by limiting the pericellular release of bradykinin from surface-bound kininogens: a survival strategy based on the silencing of proinflammatory G-protein coupled kinin [B.sub.2] and [B.sub.1] receptors
During normal contact activation (caused by tissue damage), activated factor 12 cleaves prekallikrein to kallikrein which then leads to bradykinin formation.
Successful perioperative management of a patient with C1 esterase inhibitor deficiency with a novel bradykinin receptor B2 antagonist
The kallikrein-kinin cascade is stimulated as a result of activated kallikrein (or Hageman factor/Factor XII and prekallikrein), or microbial proteases cleave off bradykinin directly from either high-molecular-weight or low-molecular-weight kininogen in the plasma (3-11,13) which causes pain and extravasation.
Vascular permeability in cancer and infection as related to macromolecular drug delivery, with emphasis on the EPR effect for tumor-selective drug targeting
Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis.
Association of FXII 5'UTR 46C>T polymorphism with FXII activity and risk of thrombotic disease/FXII 5'UTR 46C>T polimorfizmi ile FXII aktivitesi ve trombotik hastalik riskinin iliskisi

Encyclopedia browser ?
Full browser ?